Results 201 to 210 of about 16,333 (259)

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Efficacy of Stem Cell-Derived Exosomes in Promoting Diabetic Foot Ulcer Healing: A Meta-Analysis of Preclinical Animal Studies. [PDF]

J Diabetes Res
Wang X, Pan L, Shen H.
europepmc   +1 more source

Understanding exosomes in diabetic wound healing

Periodontology 2000, EarlyView.
Abstract Background Diabetic wounds signify a major complication of diabetes mellitus, characterized by chronic inflammation, compromised angiogenesis, and high risk of infection, amputation, and mortality. Contemporary therapies remain limited in efficacy and durability.
Paras Ahmad, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +4 more
wiley   +1 more source

Endothelial soluble APP/APLP2 promote heart repair through KIT-mediated angiogenesis. [PDF]

Sci Adv
Kawase H, Liu S, Kurz S, Bengelsdorff V, Bonnavion R, Jin YJ, Roquid KA, Cho H, Liang G, Banićević M, Shiva N, Yunes-Leites PS, Günther S, Tombor L, Dimmeler S, Looso M, Mattonet K, Wettschureck N, Müller UC, Offermanns S.   +19 more
europepmc   +1 more source

Understanding Exosomes in Hair Regeneration

Periodontology 2000, EarlyView.
Abstract Background Alopecia is a prevalent condition correlated with significant psychosocial challenges, while contemporary treatments exhibit variable efficacy, require extended use, and may cause adverse effects. This review aimed to comprehensively assess exosome‐mediated interventions as a novel cell‐free regenerative approach for hair ...
Paras Ahmad, Catherine Davies, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Zinc- and fluoride-containing bioactive glass enhances angiogenesis-mediated bone regeneration via M2d macrophage activation. [PDF]

Sci Rep
Otake K, Kondo T, Kakinuma H, Sato Y, Ambo S, Ashry A, Engkatanachai K, Sato J, Egusa H.   +8 more
europepmc   +1 more source

Surgical considerations based on oral and periodontal vascularization

Periodontology 2000, EarlyView.
Abstract Objectives To synthesize current evidence on vascular and anastomotic patterns, emphasizing their operative implications for optimizing flap perfusion, neovascularization, and wound healing in periodontal and implant surgery, while accounting for anatomical variability and collateral circulation. Materials and Methods A comprehensive review of
Arvin Shahbazi, Edward P. Allen, Sebastian Gschwindt, Kevin G. Murphy, Gábor Baksa, Anton Sculean   +5 more
wiley   +1 more source

The effect of amlodipin, a calcium channel blocker, on tendon healing: an experimental study in rat model of Achilles tendon injury. [PDF]

Eur J Trauma Emerg Surg
Karapinar SE, Duvarci UC, Tunc S, Sarıısık UU, Topcu OF, Dincer R, Cepni SK, Yonet AG, Armagan I, Imeci OB, Asci H.   +10 more
europepmc   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source