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The impaired hindlimb revascularization of Id1+/−, Id3−/− mutant supports a role for bone-marrow derived progenitor cells in physiologic neovascularization

Journal of the American College of Surgeons, 2004
Abstract Introduction: Increasing evidence suggests the importance of bone-marrow derived progenitor cells in angiogenesis. However, the exact role of the progenitor cells in hindlimb revascularization is unknown. In order to determine if endothelial progenitor cells are necessary for hindlimb revascularization, we used Id1+/−, Id3−/− mutant mouse ...
Yuki Sakai, Darren Schneider
openaire   +1 more source

Pleiotropic Effects of YC-1 Selectively Inhibit Pathological Retinal Neovascularization and Promote Physiological Revascularization in a Mouse Model of Oxygen-Induced Retinopathy

Molecular Pharmacology, 2010
Vascular endothelial growth factor (VEGF) and inducible nitric-oxide synthase (iNOS) have been implicated in ischemia-induced retinal neovascularization. Retinal ischemia has been shown to induce VEGF and iNOS expression. It has been postulated that one of the crucial consequences of iNOS expression in the ischemic retina is the inhibition of ...
M, DeNiro   +4 more
openaire   +2 more sources

Endothelial Cell Derived Stromal-Derived Factor-1 (SDF-1) Regulates Neovascularization and Fibroblast Physiology in Response to Ischemia

Journal of the American College of Surgeons, 2014
Zeshaan N. Maan   +9 more
openaire   +1 more source

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