Results 171 to 180 of about 89,651 (269)

The Use of Intravenous Clonidine in Postoperative Pain Management: A Scoping Review

open access: yesActa Anaesthesiologica Scandinavica, Volume 70, Issue 9, October 2026.
ABSTRACT Background Clonidine, an alpha‐2 receptor agonist, has been explored as a potential analgesic in postoperative pain management, but its efficacy and safety profile remain unclear. The aim of this scoping review was to present the evidence on the use of intravenous clonidine in postoperative pain management.
Tórálvur Mohr   +4 more
wiley   +1 more source

Nationwide utilization patterns and perioperative outcomes of minimally invasive pediatric nephrectomy in Germany. [PDF]

open access: yesFront Pediatr
Weidner J   +9 more
europepmc   +1 more source

Trends in kidney stone disease: a 5‐year update of stone management in England and Scotland

open access: yesBJU International, Volume 138, Issue 4, Page 620-629, October 2026.
Objectives To describe contemporary trends in kidney stone disease (KSD)‐related inpatient episodes, procedures, and costs in England and Scotland, with emphasis on post‐coronavirus disease 2019 (COVID‐19) service recovery, socioeconomic variation in Scotland, comparison with other urological procedures, and 10‐year healthcare demand and cost ...
Catherine E. Lovegrove   +4 more
wiley   +1 more source

Sodium Butyrate Attenuates Renal Fibrosis by Regulating Glycolysis and Histone H4K12 Lactylation in Diabetic Kidney Disease

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9518-9534, October 2026.
ABSTRACT Background The role of histone lactylation in diabetes associated renal fibrosis remains poorly defined. In this study, we investigated the contribution of histone H4 lysine 12 lactylation (H4K12la) to abnormal glycolysis and renal fibrogenesis in diabetic kidney disease (DKD) and evaluated sodium butyrate (NaB) as a potential therapeutic ...
Ping He   +10 more
wiley   +1 more source

Updates and controversies in contemporary grading of clear cell renal cell carcinoma and papillary renal cell carcinoma

open access: yesHistopathology, Volume 89, Issue 4, Page 574-589, October 2026.
New concepts, innovations and some issues have emerged since the adoption a decade ago of WHO/ISUP grading for CCRCC and PRCC. Continued use of the WHO/ISUP grading for CCRCC and PRCC has been upheld by newer studies, and practice guidance for some of the grading issues, where data are available, is provided.
Gladell P. Paner   +4 more
wiley   +1 more source

Development of an Improved Cadaveric Training Model for Endoscopic Combined Intrarenal Surgery Using Fresh‐Frozen Cadavers

open access: yesInternational Journal of Urology, Volume 33, Issue 10, October 2026.
ABSTRACT Objectives Endoscopic combined intrarenal surgery (ECIRS) is technically demanding and has a prolonged learning curve. Reports describing ECIRS training using fresh‐frozen cadavers are limited, partly because intrarenal and pyelovenous backflow may prevent adequate hydronephrosis. This study aimed to establish an optimized ECIRS training model
Keito Shiozaki   +19 more
wiley   +1 more source

S14G‐humanin attenuates renal ischaemia–reperfusion injury, potentially through activation of STAT3 and ERK1/2 signalling pathways in rats

open access: yesExperimental Physiology, Volume 111, Issue 10, Page 4915-4927, 1 October 2026.
Abstract Renal ischaemia–reperfusion (I/R) injury leads to acute tubular necrosis and renal failure, triggering pathological mechanisms including inflammation, reactive oxygen species generation, apoptosis and mitochondrial dysfunction. The mitochondrial peptide humanin (HN), known to possess anti‐apoptotic and anti‐inflammatory properties, has been ...
Leyla Abueid   +4 more
wiley   +1 more source

Slow calcium removal contributes to impaired lusitropic response to β‐adrenergic stimulation in HFpEF mice

open access: yesThe Journal of Physiology, Volume 604, Issue 20, Page 8345-8359, 15 October 2026.
Abstract figure legend Heart failure with preserved ejection fraction (HFpEF) is the most common form of heart failure, yet major gaps remain in our understanding of its underlying mechanisms, disease progression and effective treatment strategies. Mice with HFpEF exhibited exercise intolerance and diastolic dysfunction in vivo, while isolated hearts ...
Tamzin Zawadzki   +6 more
wiley   +1 more source

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