Results 151 to 160 of about 8,337 (255)

Unveiling the immune landscape and microenvironmental architecture of IgA nephropathy using single‐cell imaging mass cytometry

open access: yesClinical &Translational Immunology, Volume 15, Issue 3, 2026.
In IgA nephropathy (IgAN), innate and adaptive immune cells display distinct spatial compartmentalisation, with macrophages predominating within glomeruli and CD4+ T cells constituting the major immune population in inflammatory foci. Glomeruli with distinct pathological morphologies exhibit morphology‐dependent immune infiltration patterns and ...
Xing Chen   +8 more
wiley   +1 more source

Decreasing Serum Adropin Levels in Patients With Systemic Lupus Erythematosus: A Case‐Control Study

open access: yesHealth Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Introduction Systematic lupus erythematosus is a complex fundamental autoimmune disease with relapsing‐remitting course and spectrum of disease ranging from mild to life‐threatening illness. Approximately half of women diagnosed with systemic lupus erythematosus (SLE) are affected by obesity, with rates reaching up to 50%.
Mehrzad Hajialilo   +5 more
wiley   +1 more source

Karyomegalic interstitial nephritis: A case series and review of the literature on genetic insights and clinical challenges. [PDF]

open access: yesClin Nephrol Case Stud
Ozcan SG   +6 more
europepmc   +1 more source

Association Between Inflammatory Cytokines and Systemic Inflammation Indices in Patients With Psoriasis: A Cross‐Sectional Study

open access: yesHealth Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Objectives Systemic inflammation indices derived from complete blood counts (CBC) are accessible markers of inflammatory burden, but their relationship with circulating cytokines in psoriasis remains unclear. We investigated associations between CBC‐derived indices and serum cytokines in psoriasis.
Luca Schneller‐Pavelescu   +5 more
wiley   +1 more source

Akkermansia muciniphila enhances chicken resistance to infectious bronchitis virus by boosting GABA synthesis and suppressing the NF‐κB inflammatory pathway

open access: yesiMetaOmics, Volume 3, Issue 1, March 2026.
Infectious bronchitis virus (IBV) represents a major threat to poultry production, with current control strategies offering limited protection. In this study, we demonstrate gut microbiome is a critical determinant of IBV resistance using fecal microbiota transplantation.
Ouyang Peng   +22 more
wiley   +1 more source

Integrative Genomics Reveals Causal Pleiotropy and Therapeutic Opportunities at the Interface of Acute Pancreatitis and Infection

open access: yesJournal of Hepato-Biliary-Pancreatic Sciences, Volume 33, Issue 3, Page 194-207, March 2026.
ABSTRACT Background Understanding the genetic links between acute pancreatitis (AP) and its infectious comorbidities is crucial for prognosis and therapy, yet remains underexplored. Methods We conducted a comprehensive post‐GWAS analysis using large‐scale summary statistics for AP and 16 infectious diseases. To pinpoint pleiotropic genes, we integrated
Bo Zou   +6 more
wiley   +1 more source

Trans‐Omics Integration Reveals That the Kidney Contributes to Systemic Aging via Sexually Dimorphic Accumulation of Glycosphingolipids

open access: yesMedComm, Volume 7, Issue 3, March 2026.
Female‐specific renal GluCer accumulation disrupts mitochondrial quality control via a conserved purine‐mTORC1 pathway, triggering a wave of uremic toxins into the systemic circulation that constitutes a female‐biased vulnerability toward renal‐driven multiorgan senescence.
Zhen Ni   +18 more
wiley   +1 more source

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