Results 91 to 100 of about 50,580 (242)

A prospective observational study of mycophenolate mofetil treatment in progressive diffuse cutaneous systemic sclerosis of recent onset. [PDF]

, 2012
OBJECTIVE: A prospective observational study of mycophenolate mofetil (MMF) treatment in patients with diffuse progressive cutaneous systemic sclerosis (SSc) of recent onset.
Jimenez, Sergio A., Lee, MD, Jason B., Mendoza, MD, Fabian A., Nagle, Sarah J.   +3 more
core   +3 more sources

Evolving treatments for Sjögren disease: current approaches and emerging targets

Internal Medicine Journal, EarlyView.
Abstract Sjögren disease (SjD) is a prevalent systemic autoimmune condition characterised by exocrine gland dysfunction, systemic inflammation and heterogeneous organ involvement. Current management remains largely symptomatic, with no approved disease‐modifying therapies available and substantial unmet clinical need. However, advances in understanding
Mansi Bhurani, Adrian Y. S. Lee, Maureen Rischmueller, Alberta Hoi   +3 more
wiley   +1 more source

Acute tubulo-interstitial nephritis leading to acute renal failure following multiple hornet stings

BMC Nephrology, 2006
Background Hornet stings are generally associated with local and occasionally anaphylactic reactions. Rarely systemic complications like acute renal failure can occur following multiple stings. Renal failure is usually due to development of acute tubular
Bambery Pradeep, Sakhuja V, Mahesha V, Wanchu Ajay, Sharma Aman, Singh Surjit   +5 more
doaj   +1 more source

Chemokine receptor CCR1: A new target for progressive kidney disease [PDF]

, 2005
Infiltrating leukocytes are thought to contribute to the progression of kidney disease. Locally produced chemokines guide circulating leukocytes into the kidney, which renders therapeutic blockade of respective chemokine receptors on the leukocyte ...
Anders, Hans-Joachim, Ninichuk, Volha
core   +1 more source

The emergence of pathogens on fish in an impacted estuary and the role of non‐native piranhas in a potential bacterial infectious outbreak

Journal of Fish Biology, EarlyView.
Abstract As many tropical aquatic ecosystems worldwide, the Doce River estuary (DRE, southeastern Brazil) has increasingly faced multiple anthropogenic threats, including deforestation, mining, species introduction and water management. The 2015 collapse of the Fundão iron ore tailings dam severely changed water properties and increased heavy metal ...
Ryan Andrades, Helder C. Guabiroba, Kathiani V. Bastos, Vítor L. A. Rodrigues, Marcelo R. D. Santos, Clarisse M. Arpini, Mayra Cunha Flecher, Helen A. Pichler, Ciro C. Vilar, Maurício Hostim‐Silva, Jean‐Christophe Joyeux   +10 more
wiley   +1 more source

Reduced CD40L expression on ex vivo activated CD4+T-lymphocytes from patients with excellent renal allograft function measured with a rapid whole blood flow cytometry procedure [PDF]

, 2004
Background: The CD40-CD40L (CD154) costimulatory pathway plays a critical role in the pathogenesis of kidney allograft rejection. In renal transplant biopsies, CD4+ CD40L+ graft-infiltrating cells were detected during chronic rejection in contrast to ...
Friedrich, N., Gruber, R., Landgraf, R., Lederer, Stephan R., Sitter, Thomas, Toepfer, Marcel   +5 more
core   +1 more source

GLP‐1 Receptor Agonists and Weight Loss: A Critical Review of Mechanisms

Obesity Reviews, EarlyView.
ABSTRACT GLP‐1 receptor agonist medications have the potential to promote marked weight loss, but maximal and sustained benefit may be compromised by poor compliance and cessation of use. Development of next‐generation medications that address current obstacles to effective use and development of effective adjunct treatments will benefit from better ...
Giorgia Rutigliani, Tzu‐Wen L. Cross, Erica de Jong, Emily S. Glover, Ivan D. Mendoza, Mojisola Adisa, Keigo Tomoo, Xinyi Zhou, Richard D. Mattes   +8 more
wiley   +1 more source

Acute interstitial nephritis and drug-induced systemic lupus erythematosus due to chlorthalidone and amiodarone: A case report

SAGE Open Medical Case Reports, 2020
Drug-induced lupus erythematosus has features distinct from primary systemic lupus erythematosus. It can occur with a wide variety of agents that result in the generation of anti-histone or other types of antibodies.
Umut Selamet, Ramy M Hanna, Anthony Sisk, Lama Abdelnour, Lena Ghobry, Ira Kurtz   +5 more
doaj   +1 more source

Decay-Accelerating Factor 1 Deficiency Exacerbates Leptospiral-Induced Murine Chronic Nephritis and Renal Fibrosis [PDF]

, 2014
Leptospirosis is a global zoonosis caused by pathogenicLeptospira, which can colonize the proximal renal tubules andpersist for long periods in the kidneys of infected hosts.
Alberdi, Maria Lucrecia, Cédola, Maia Tatiana, Drut, Ricardo, Ferrer, Maria Florencia, Gomez, Ricardo Martin, Prêtre, Gabriela, Scharrig Fernandez, Maria Emilia, Song, Wen-Chao   +7 more
core   +1 more source

Comparative 3‐Year Allograft Outcomes for Recipients of Kidneys From SARS‐CoV‐2 NAT‐Positive Donors

Transplant Infectious Disease, EarlyView.
In this retrospective single‐center study of 220 kidney transplants from SARS‐CoV‐2 NAT+, NAT+ with COVID as cause of death (CoV‐COD) and NATneg donors, we found no significant difference in rejection or kidney pathologies at 1 year, and death, graft loss, or eGFR at 3 years by CoV‐donor status.
Christine E. Koval, Mohamed Eltemamy, Nabin K. Shrestha, Leal Herlitz, Emilio D. Poggio, Alvin C. Wee   +5 more
wiley   +1 more source