Results 61 to 70 of about 50,580 (242)
Rifampicin induced acute interstitial nephritis in a patient with tuberculosis: A case report
Asian Journal of Internal Medicine, 2023 Interstitial nephritis is a rare complication of anti-tuberculosis treatment, most commonly rifampicin. This case report describes a 65-year-old woman with diabetes who presented with loss of consciousness due to a major hypoglycemic episode precipitated
S. Sureshkumar +5 more
doaj +1 more source
Inhibiting ERK Activation with CI-1040 Leads to Compensatory Upregulation of Alternate MAPKs and Plasminogen Activator Inhibitor-1 following Subtotal Nephrectomy with No Impact on Kidney Fibrosis [PDF]
, 2015 Extracellular-signal regulated kinase (ERK) activation by MEK plays a key role in many of the cellular processes that underlie progressive kidney fibrosis including cell proliferation, apoptosis and transforming growth factor β1-mediated epithelial to ...
AA Eddy +50 more
core +2 more sources
Arthritis &Rheumatology, EarlyView.Sjögren disease (SjD) is a common systemic autoimmune disorder characterized by inflammation of the exocrine glands, resulting in dryness. Patients frequently exhibit extraglandular manifestations affecting various organ systems. To date, there are no US Food and Drug Administration (FDA)‐approved disease‐modifying therapies for SjD. In this review, we
Rachael A. Gordon, Sara S. McCoy
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective Immune complexes (ICs), formed by autoantigen and autoantibody, play a pathogenic role in systemic autoimmune diseases through stimulation of Fcγ receptors (FcγR). However, studies investigating bioactivity of circulating ICs across various diseases remain limited.
Koji Suzuki +8 more
wiley +1 more source
European Journal of Medical Research, 2022 Background Acute interstitial nephritis (AIN) is an important cause of kidney injury accounting for up to 27% of unexplained renal impairment. In up to 70% of cases, drugs, including aminosalicylates, are reported as the underlying cause.
James G. Moss +3 more
doaj +1 more source
Mesalazine-associated interstitial nephritis [PDF]
Nephrology Dialysis Transplantation, 1996 Abstract Background. When used for oral treatment of inflammatory bowel disease, Asacol (a coated form of mesalazine = 5-aminosalicylic acid) can cause interstitial nephritis. The spectrum of severity, frequency of occurrence and the best renal function test to detect this complication are not ...
M J, World +3 more
openaire +2 more sources
Arthritis &Rheumatology, Accepted Article.Objectives The hematopoietic system maintains homeostasis by balancing myeloid and lymphoid cell production in the bone marrow (BM). In response to increased hematopoietic demand, extramedullary hematopoiesis (EMH) may occur in non‐lymphoid organs. We investigated the role of EMH and kidney‐resident hematopoietic stem and progenitor cells (HSPCs) in ...
Hansol Yi +9 more
wiley +1 more source
Acute interstitial nephritis with Prothionamide
SAGE Open Medical Case Reports, 2022 Among drug-related complications, drug-related nephrotoxicity is the commonest. It is the cause for 7% of all drug-related toxicities among inpatients and accounts for 20% to 30% of acute renal failure.
Molla Asnake +6 more
doaj +1 more source
Recent advances in the understanding of renal inflammation and fibrosis in lupus nephritis [PDF]
, 2017 published_or_final_versio
Chan, DTM, Yap, YHD, Yung, SSY
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims In medical education, the ability of large language models (LLMs) to match human performance raises questions about their potential as educational tools. This study evaluates LLMs' performance on Clinical Pharmacology and Therapeutics (CPT) exams, comparing their results to medical students and exploring their ability to identify poorly formulated
Alexandre O. Gérard +11 more
wiley +1 more source