Results 121 to 130 of about 224,992 (367)

Sensitivity and Specificity of Pathologic Findings to Diagnose Lupus Nephritis.

American Society of Nephrology. Clinical Journal, 2019
BACKGROUND AND OBJECTIVES In 2012, the Systemic Lupus International Collaborating Clinics proposed that lupus nephritis, in the presence of positive ANA or anti-dsDNA antibody, is sufficient to diagnose SLE.
Satoru Kudose, D. Santoriello, A. Bomback, M. Stokes, V. D’Agati, G. Markowitz   +5 more
semanticscholar   +1 more source

War Nephritis [PDF]

The American Journal of the Medical Sciences, 1917
n ...
openaire   +2 more sources

Complement in nephritis [PDF]

Postgraduate Medical Journal, 1973
Evidence for complement involvement in glomerulonephritis Clinical measurements In acute nephritis the serum level of complement is usually reduced, often to one-tenth of normal. This reduction is short lived and within 2-3 weeks the complement concentration returns to normal (Fig. 1).
openaire   +3 more sources

Indication‐Specific Dosing and Dose‐Evaluation Strategies in New Indications for Non‐Oncology Monoclonal Antibodies

The Journal of Clinical Pharmacology, EarlyView.
Abstract Compared to traditional small molecule drugs, monoclonal antibodies (mAbs) often display more complex pharmacokinetic (PK) and pharmacodynamic (PD) properties that may be impacted by disease‐specific factors. For mAbs in non‐oncology indications, where the same drug might be used for conditions involving different organ systems and/or having ...
Sherouk M. Tawfik, Fei Tang
wiley   +1 more source

Reduced expressions of apoptosis-related proteins TRAIL, Bcl-2, and TNFR1 in NK cells of juvenile-onset systemic lupus erythematosus patients: relations with disease activity, nephritis, and neuropsychiatric involvement

Frontiers in Immunology
BackgroundLupus pathogenesis is mainly ascribed to increased production and/or impaired clearance of dead cell debris. Although self-reactive T and B lymphocytes are critically linked to lupus development, neutrophils, monocytes, and natural killer (NK ...
Bernadete L. Liphaus, Bernadete L. Liphaus, Simone C. Silva, Patrícia Palmeira, Clovis A. Silva, Clovis A. Silva, Claudia Goldenstein-Schainberg, Magda Carneiro-Sampaio   +7 more
doaj   +1 more source

Immunosuppressive treatment for proliferative lupus nephritis.

Cochrane Database of Systematic Reviews, 2018
BACKGROUND Cyclophosphamide, in combination with corticosteroids, has been first-line treatment for inducing disease remission for proliferative lupus nephritis, reducing death at five years from over 50% in the 1950s and 1960s to less than 10% in recent
D. Tunnicliffe, S. Palmer, L. Henderson, P. Masson, J. Craig, A. Tong, D. Singh-Grewal, R. Flanc, M. Roberts, A. Webster, G. Strippoli   +10 more
semanticscholar   +1 more source

Association of In Vivo Kidney Stiffness Measured by Multifrequency MR Elastography and Long‐Term Renal Function in Transplant Recipients and Living Donors

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Kidney transplant (KTx) function assessment is important in treatment planning, while conventional MRI markers lack sensitivity for KTx function. Mechanical kidney properties may serve as MRI markers for renal allograft function. Hypothesis To determine if multifrequency MR elastography (MRE) is associated with KTx function.
Stephan Rodrigo Marticorena Garcia, Jonas Oppenheimer, Tom Meyer, Frank Friedersdorff, Ingolf Sack   +4 more
wiley   +1 more source

Annus Mirabilis - a guide to the 6th European Lupus meeting 3-5 March 2005 [PDF]

, 2005
This article has no ...
Bowman, S.J., Giles, I.P., Ioannou, Y., Isenburg, D.A., Rahman, A.   +4 more
core  

Positron emission tomography as an adjuvant diagnostic test in the evaluation of checkpoint inhibitor-associated acute interstitial nephritis

Journal of Immunotherapy for Cancer, 2019
BackgroundAcute interstitial nephritis is an immune-related adverse event that can occur in patients receiving immune checkpoint inhibitor therapy. Differentiating checkpoint inhibitor-associated acute interstitial nephritis from other causes of acute ...
David Qualls, H. Seethapathy, Halla Bates, Shahein H. Tajmir, P. Heidari, P. Endres, K. Reynolds, D. Lawrence, M. Sise   +8 more
semanticscholar   +1 more source

The Diagnostic Value of Contrast‐Enhanced Vessel Wall MRI for Diagnosing Neuropsychiatric Systemic Lupus Erythematosus

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Imaging biomarkers for neuropsychiatric systemic lupus erythematosus (NPSLE) are highly needed, and intracranial contrast‐enhanced vessel wall imaging (CE‐VWI) can potentially detect cerebral vessel wall abnormalities in lupus. Purpose To evaluate the diagnostic value of CE‐VWI in differentiating NPSLE from non‐NPSLE.
Satoru Ide, Yuya Fujita, Yu Murakami, Koichiro Futatsuya, Yuta Yoshimatsu, Jun Tsukamoto, Haruka Oku, Toshihiro Sakamoto, Yoshiya Tanaka, Takatoshi Aoki   +9 more
wiley   +1 more source