Results 121 to 130 of about 173,599 (327)

IgA Vasculitis in a Lung Cancer Patient During Chemoradiotherapy

Therapeutics and Clinical Risk Management, 2021
Masataka Taoka,1 Nobuaki Ochi,1 Ayaka Mimura,1 Naruhiko Ichiyama,1 Yasunari Nagasaki,1 Nozomu Nakagawa,1 Hidekazu Nakanishi,1 Hiromichi Yamane,1 Yoshiyuki Oshiro,2 Yasumasa Monobe,3 Nagio Takigawa1 1Department of General Internal Medicine 4, Kawasaki ...
Taoka M, Ochi N, Mimura A, Ichiyama N, Nagasaki Y, Nakagawa N, Nakanishi H, Yamane H, Oshiro Y, Monobe Y, Takigawa N   +10 more
doaj  

Clinical Safety of Extended Interval Dosing of Nivolumab in Patients with Melanoma

Clinical Pharmacology &Therapeutics, EarlyView.
Extended interval dosing regimens of immune checkpoint inhibitors have been implemented widely. However, their approval was mainly based on pharmacokinetic modeling and simulations. Consequently, comparative safety data of extended interval dosing regimens in a real‐world setting are limited.
Ruben Malmberg, Maaike M. Hofman, Fatima Ashad, Alaa Daloul, Stefani Oosterveld, Edwin A. Basak, Esther Oomen‐de Hoop, Astrid A. M. van der Veldt, Arjen Joosse, Roelof W. F. van Leeuwen, Ron H. J. Mathijssen   +10 more
wiley   +1 more source

The Effect of Arabic Gum on Gentamicin Nephrotoxicity in Mice: A Pathological Study

Medicinski Glasnik
Aim To investigate the effect of Arabic gum on gentamycin nephrotoxicity in mice kidney.Methods Forty (40) mice were divided into five groups, eight mice in each. Group one (G1) stands for the negative control group. The second one (G2) was injected with
Liqaa Alhyali, Firas Abed, Entisar AL-Kenanny   +2 more
doaj   +1 more source

Real‐world efficacy and toxicity of ipilimumab and nivolumab as a first‐line treatment for advanced renal cell carcinoma according to IMDC risk criteria—A multi‐center retrospective analysis on behalf of the GUARDIANS group

International Journal of Cancer, EarlyView.
What's New? The combination of ipilimumab and nivolumab as a first‐line treatment for advanced renal cell carcinoma has demonstrated durable response and tolerability in clinical trials. However, inclusion criteria for clinical studies are restrictive, and patients in the real‐world setting tend to have more comorbidities.
Hendrik Dinkel, Linus Materna, Ramona Stelmach, Stefanie Zschäbitz, Stephanie Neuberger, Can D. Aydogdu, Jozefina Casuscelli, Timo Egenolf, Matteo Silberg, Julie Steinestel, Arne Strauss, Florian Kirchhoff, Marit Ahrens, Pia Paffenholz, Richard Cathomas, Berna C. Özdemir, Christopher Gossler, Philipp Ivanyi, Marc Rehlinghaus, Thomas Hilser, Viktor Grünwald, Katrin Schlack   +21 more
wiley   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

Evaluation of Serum Complement Components in Pediatric IgA Vasculitis: A Case-Control Study

Children
Background: IgA vasculitis (IgAV) represents the most frequently seen form of vasculitis among children. Although it often resolves without intervention, renal involvement (IgAV nephritis) poses a risk for long-term complications. Although the lectin and
Raziye Burcu Taşkın, Güzide Aksu, Sait Şen, Gülden Hakverdi, Burçe Emine Dörtkardeşler, Secil Conkar Tunçay   +5 more
doaj   +1 more source

Integrative Genomics Reveals Causal Pleiotropy and Therapeutic Opportunities at the Interface of Acute Pancreatitis and Infection

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background Understanding the genetic links between acute pancreatitis (AP) and its infectious comorbidities is crucial for prognosis and therapy, yet remains underexplored. Methods We conducted a comprehensive post‐GWAS analysis using large‐scale summary statistics for AP and 16 infectious diseases. To pinpoint pleiotropic genes, we integrated
Bo Zou, Hao Jiang, Jingsheng Ruan, Daifeng Yang, Xing Chen, Shanshan Cai, Xinglin Yi   +6 more
wiley   +1 more source

A Pathway to High Quality Clinical Trials in IgA Vasculitis Nephritis: Meeting Proceedings From a Multiprofessional International Collaborative Workshop

Kidney International Reports
IgA vasculitis (IgAV) is an autoimmune disease that affects the small vessels of the skin, joints, gastrointestinal (GI) tract, and kidneys. In the long term, IgAV associated with nephritis (IgAV-N) can progress to kidney failure. Evidence-based clinical
Louise Oni, Rona Smith, Seza Ozen, Chloe Williams, Elin Davies, Charlotte King, Paul Brogan, Mark Haas, Jonathan Barratt, Jeffrey Hafkin, Despina Eleftheriou, Karuna Keat, EMD Smith, Wen Ding, Chee Cheung, Caroline Platt, Evangéline Pillebout, Andrew Chetwynd, Areefa Alladin, Augusto Vaglio, Caroline Jones, Clare Pain, Cord Sunderkötter, John Peipert, Emily Barnes, Giorgio Trivioli, Hayley Hardwick, Henry Morgan, Ingeborg Bajema, James Wason, Joshua Wade, Judith Sanchez-Manubens, Kelly Vernon, Lisa Willcocks, Lorraine Harper, Lowena Lindsay, Madalina Andreea Beldie, Matko Marlais, Michelle O’Shaughnessy, Panagoula Gkargkoula, Patrick Hamilton, Reima Bakry, Roxana Bogos, Selcan Demir, Silke Brix, Simone Appenzeller, Tarun Bansal, Zoi Anastasa, Stephen David Marks, Alexandra Audemard-Verger, Thomas Renson, Marija Jelusic, David Jayne, Alan Salama   +53 more
doaj   +1 more source

Coexistence of Lupus Nephritis, Ulcerative Colitis, and Communicating Hydrocephalus: A Report of a 21-Year-Old Male [PDF]

, 2022
Bushra Ali Khan, Nida Saleem, Danyal Hassan, Shabaz Kiani, Muhammad Haneef   +4 more
openalex   +1 more source

Síndrome nefrítico asociado a glomerulonefritis por infección

Revista GICOS
El síndrome nefrítico secundario a glomerulonefritis relacionada con infección, es un cuadro clínico caracterizado por hematuria de origen glomerular, disminución del volumen urinario, y proteinuria que se acompaña con edemas e hipertensión arterial; el ...
Alexandra Dewdney, Jesús Mora, Aaron Saavedra, Diana Rodríguez, Dulce Winterdaal   +4 more
doaj   +1 more source