Results 151 to 160 of about 112,843 (300)
Features and outcomes of lupus nephritis in Morocco: analysis of 114 patients
, 2013 Intissar Haddiya,1 Hakim Hamzaoui,1 Nabil Tachfouti,2 Zitouna Al Hamany,3 Aicha Radoui,1 Najoua Zbiti,1 Yamama Amar,1 Hakima Rhou,1 Loubna Benamar,1 Naima Ouzeddoun,1 Rabea Bayahia1 1Department of Nephrology, Dialysis, and Renal Transplantation, Ibn Sina
Tachfouti N +10 more
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Fn14 signalling participates in pristane‐induced murine lupus through exacerbating oxidative stress
British Journal of Pharmacology, EarlyView.Background and Purpose Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by oxidative stress and immune dysregulation. Fibroblast growth factor‐inducible 14 (Fn14) has been implicated in tissue injury, but its specific role in SLE pathogenesis remains unclear.
Zhu Yan +8 more
wiley +1 more source
A rare case of transition to membranous lupus nephritis from diffuse proliferative lupus nephritis
, 2014 publisher[Abstract] Lupus nephritis is an important complication of systemic lupus erythematosus (SLE) that affects the prognosis. A rare type of lupus nephritis, class V, shows histological findings resembling those of membranous nephropathy. While most
ニシ, ヒトミ +17 more
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Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aims Urogenital adverse events are common with sodium‐glucose co‐transporter 2 inhibitors (SGLT2i) and may influence treatment decisions. Variations in SGLT2i selectivity, potency and effects on renal glucose excretion could lead to differences in safety profiles. We compared the risks of urinary tract infection (UTI), genital tract infection (
Christine Ljungberg +7 more
wiley +1 more source
Autologous Epstein–Barr virus-specific adoptive T-cell therapy in a patient with lupus nephritis
Objectives Dysregulation of Epstein–Barr virus (EBV)-specific cellular immunity has been hypothesised as one of the contributing factors in the pathogenesis of systemic lupus erythematosus (SLE).
John, George T +13 more
core +1 more source
Proteolytic remodelling of the extracellular matrix by pericytes
The FEBS Journal, EarlyView.Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard +4 more
wiley +1 more source
Histopathology, EarlyView.Glomerular plasmalemma vesicle‐associated protein‐1 (PV‐1/PLVAP) identifies dynamic endothelial remodelling in chronic active antibody‐mediated rejection (caABMR), complementing glomerular C4d, which reflects a static footprint of complement activation. Combined assessment of PV‐1 and C4d captures complementary dimensions of microvascular pathology and
Yuto Igarashi +7 more
wiley +1 more source
Evolving treatments for Sjögren disease: current approaches and emerging targets
Internal Medicine Journal, EarlyView.Abstract Sjögren disease (SjD) is a prevalent systemic autoimmune condition characterised by exocrine gland dysfunction, systemic inflammation and heterogeneous organ involvement. Current management remains largely symptomatic, with no approved disease‐modifying therapies available and substantial unmet clinical need. However, advances in understanding
Mansi Bhurani +3 more
wiley +1 more source