Results 211 to 220 of about 173,599 (327)

First‐in‐Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ASP1617, a Cathepsin‐S Inhibitor, in Healthy Adult Subjects

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT ASP1617 is a novel, highly selective inhibitor of cathepsin‐S, an important protease for antigen peptide loading onto major histocompatibility complex class II molecules. Preclinically, ASP1617 prevented progression of lupus‐like glomerulonephritis in an NZB/W F1 mouse model of systemic lupus erythematosus.
Tomoki Kojima, Wei Chen, Ronald Smulders, Stephen Stanhope, Donna Kowalski, Nakyo Heo, Selina Moy, Amanda Goldston, David Han, Tong Zhu   +9 more
wiley   +1 more source

Tubulointerstitial nephritis and uveitis syndrome: an unexpected diagnosis. [PDF]

BMJ Case Rep
Farnan R, Leavey S, Stokes J, Casey R.
europepmc   +1 more source

Efficacy and safety of glucagon‐like peptide 1 receptor agonists across all health outcomes in type 2 diabetes: An umbrella review and evidence map of randomised controlled trials

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 1136-1149, February 2026.
Abstract Aim Glucagon‐like peptide 1 receptor agonists (GLP‐1RAs) have been established as effective treatments for type 2 diabetes, offering benefits beyond glycaemic control; however, their associations across multiple health outcomes remain insufficiently assessed.
Dongjin Yeo, Yeona Jo, Jinyoung Jeong, Yi Deun Jeong, Ho Geol Woo, Yejun Son, Sunyoung Kim, Sang Youl Rhee, Dong Keon Yon   +8 more
wiley   +1 more source

Clinical, humanistic, and economic burden of systemic lupus erythematosus in the Kingdom of Saudi Arabia. [PDF]

Cost Eff Resour Alloc
Al-Jedai A, Al-Mudaiheem H, Ghanim NA, Eshmawi M, AlHomood I, Dhopte P, Ojeil R.   +6 more
europepmc   +1 more source

Acute tubulointerstitial nephritis associated with infliximab therapy in a patient with Crohn’s disease: a case report [PDF]

Naif A. Alghamdi, Fahad M. Alshehri, Sultan Alhazza, Fahad Bhutto, A. A. Al‐Hassan, M Kechrid, Dhafer Alshehri, Khaled Khamees Alshammari, Talal Assiri, Ohoud Hassan Assiri, Emad Darewsh, Mohammed K. Ali, Ruba Qadri, Yaser M. Alahmadi   +13 more
openalex   +1 more source

Acute Nephritis

International Journal of Clinical Practice, 1956
openaire   +2 more sources

Risk of End‐Stage Renal Disease in Patients With Lupus Nephritis, 1971–2015: A Systematic Review and Bayesian Meta‐Analysis

Arthritis & Rheumatology, 2016
M. Tektonidou, A. Dasgupta, M. Ward
semanticscholar   +1 more source

Lupus Nephritis During the COVID-19 Pandemic: Challenges and Implications Before, During, and After. [PDF]

Biomedicines
Komorniczak M, Stępniewski P, Bułło-Piontecka B, Lisowska KA, Dębska-Ślizień A, Wardowska A.   +5 more
europepmc   +1 more source

Histologic versus clinical remission in proliferative lupus nephritis

Nephrology, Dialysis and Transplantation, 2017
A. Malvar, P. Pirruccio, V. Alberton, B. Lococo, Cecilia Recalde, Bernanda Fazini, H. Nagaraja, D. Indrakanti, B. Rovin   +8 more
semanticscholar   +1 more source

Systemic Lupus Erythematosus With Acute Inflammatory Demyelinating Polyneuropathy in Pregnancy: A Rare Multisystem Presentation. [PDF]

Cureus
Saeed H, Ur Rehman M.
europepmc   +1 more source