Results 211 to 220 of about 112,843 (300)

The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets

iNew Medicine, Volume 2, Issue 2, June 2026.
The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong, Zhenyu Wang, Suyin Yang, Kaige Gao, Xin Yang, Min Tang   +5 more
wiley   +1 more source

Management of hypogammaglobulinemia in pediatric patients with refractory lupus nephritis: a focus on belimumab. [PDF]

Front Pediatr
Han Y, Yang Y, Han P, Yuan X, Li C, Cui J.   +5 more
europepmc   +1 more source

Forsythiaside A Alleviates Kidney Injury and Intestinal Epithelium Dysfunction in IgA Nephropathy by Inhibiting TLR4/NF‐κB Signaling

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 6, June 2026.
ABSTRACT IgA nephropathy (IgAN), the most common form of glomerulonephritis, is a major and growing public health issue. It results from intestinal barrier dysfunction that leads to mesangial deposition of pathogenic galactose‐deficient IgA1 (Gd‐IgA1) and renal inflammation.
Meng‐Si Li, Kai Liu
wiley   +1 more source

Trends, pathological classification of renal diseases proved by biopsy: A 10-year retrospective cohort study in an East Chinese Tertiary Center. [PDF]

Medicine (Baltimore)
Dong R, Sun J, Guo M, Bian Q, Guo Z, Xu J.   +5 more
europepmc   +1 more source

Breaking Barriers Between Species: Integrated Multi‐Species PK Models Improve Human PK Predictions

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 6, June 2026.
ABSTRACT The accurate prediction of human pharmacokinetics (PK) is critical for compound selection and determining the human efficacious dose in drug discovery. Besides predicting the key PK parameters clearance (CL) and steady‐state distribution volume (Vss), the prediction of exposure metrics, e.g., maximum and trough concentrations (Cmax, Ctrough ...
Miriam S. R. Happ, Jens M. Borghardt, Charlotte Kloft, Hermann Rapp, Achim Sauer, Anneke Himstedt, Bettina Gerner   +6 more
wiley   +1 more source

Efficacy of the Lupus-Cruces Nephritis protocol in different prognostic groups: a propensity score and cluster analysis. [PDF]

Rheumatology (Oxford)
Ruiz-Irastorza G, Marín-García B, Dueña-Bartolomé L, Paredes-Ruiz D, Osorio A, Lázaro E.   +5 more
europepmc   +1 more source

A ‘Wholly Unjustifiable Treatment of British Subject’? The Detention of W. T. Goode in the Baltic, 1919

History, Volume 111, Issue 396, Page 386-403, June 2026.
Abstract In the summer of 1919, W. T. Goode, the Manchester Guardian’s special correspondent in Russia and the Baltic, was arrested in the Estonian capital Tallinn and briefly detained aboard a British warship. Goode's detention caused a furore, leading to accusations of kidnap, heated commentary in the press and questions in parliament.
Colin Storer
wiley   +1 more source

Cells' survival pattern of kidney macrophages and epithelial cells in lupus nephritis is influenced by glycolysis. [PDF]

Lupus Sci Med
Jativa S, Torrico S, Muñoz A, Torres Salido MT, Hotter G.   +4 more
europepmc   +1 more source

Tubulointerstitial nephritis and uveitis syndrome in children: What to keep an eye on

Acta Ophthalmologica, Volume 104, Issue 4, Page e443-e452, June 2026.
Abstract Purpose The purpose of this study was to determine the disease course in patients with tubulointerstitial nephritis and uveitis (TINU) syndrome, focusing on long‐term outcome and the incidence of complications such as chronic kidney disease (CKD).
Jytte Hendrikse, Anne Sina Paula Simon, Viera Kalinina Ayuso, Joke Helena de Boer, Gerrit van den Berg   +4 more
wiley   +1 more source