Results 91 to 100 of about 50,163 (289)

Intrauterine undernutrition - renal and vascular origin of hypertension [PDF]

, 2003
A large number of clinical and experimental studies supports the hypothesis that intrauterine undernutrition is an important determinant of hypertension, coronary heart disease and non-insulin-dependent diabetes in the adult offspring.
Carvalho, MHC, Coimbra, Terezila Machado, Fortes, Z. B., Franco, Maria do Carmo Pinho, Gil, Frida Zaladek, Gomes, Guiomar Nascimento, Lucas, Sandra Regina Rodrigues, Nigro, D., Tostes, RCA   +8 more
core   +1 more source

Periodontitis and high phosphate intake alone or in combination adversely affect the kidney

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis and high phosphate (HP) intake can negatively affect the kidney in the presence of renal disease. This study aimed to evaluate the effects of periodontitis or HP intake, either alone or concurrently, on the periodontal tissue and the kidney under normal renal conditions.
Ae Ri Kim, Min Seo Kim, Jiwon Seo, Eun‐Jung Bak, Yun‐Jung Yoo   +4 more
wiley   +1 more source

Lgr5+ve Stem/Progenitor Cells Contribute to Nephron Formation during Kidney Development

Cell Reports, 2012
Multipotent stem cells and their lineage-restricted progeny drive nephron formation within the developing kidney. Here, we document expression of the adult stem cell marker Lgr5 in the developing kidney and assess the stem/progenitor identity of Lgr5+ve ...
Nick Barker, Maarten B. Rookmaaker, Pekka Kujala, Annie Ng, Marc Leushacke, Hugo Snippert, Marc van de Wetering, Shawna Tan, Johan H. Van Es, Meritxell Huch, Richard Poulsom, Marianne C. Verhaar, Peter J. Peters, Hans Clevers   +13 more
doaj   +1 more source

Sex-specific computational models of the spontaneously hypertensive rat kidneys: factors affecting nitric oxide bioavailability [PDF]

, 2017
Sex-specific computational models of the spontaneously hypertensive rat kidneys: factors affecting nitric oxide bioavailability. Am J Physiol Renal Physiol 313: F174 –F183, 2017.
Chen, Ying, Edwards, Aurelie, Layton, Anita T., Sullivan, Jennifer C.   +3 more
core   +1 more source

Preoperative VEGFR‐TKI Plus ICI Therapy Facilitates 3D‐Guided Cytoreductive Nephron‐Sparing Surgical Feasibility and Immune Remodeling in Advanced Renal Cell Carcinoma

Med Research, EarlyView.
Preoperative VEGFR‐TKI plus ICI therapy in advanced ccRCC normalizes tumor vasculature, enhances CD8⁺ T/B cell infiltration, and promotes TLS maturation, leading to profound tumor microenvironment remodeling. These immunologic changes improve the feasibility of 3D reconstruction‐guided robotic cytoreductive nephron‐sparing surgery, resulting in reduced
Wenhao Xu, Aihetaimujiang Anwaier, Qintao Ge, Siqi Zhou, Xi Tian, Shuxuan Zhu, Guohai Shi, Yu Zhu, Dingwei Ye, Mierxiati Abudurexiti, Hailiang Zhang   +10 more
wiley   +1 more source

Quercetin treatment reduces the severity of renal dysplasia in a beta-catenin dependent manner.

PLoS ONE, 2020
Renal dysplasia, the major cause of childhood renal failure, is characterized by defective branching morphogenesis and nephrogenesis. Beta-catenin, a transcription factor and cell adhesion molecule, is markedly increased in the nucleus of kidney cells in
Joanna Cunanan, Erin Deacon, Kristina Cunanan, Zifan Yang, Antje Ask, Lily Morikawa, Ekaterina Todorova, Darren Bridgewater   +7 more
doaj   +1 more source

Bmp7は腎前駆細胞を未分化な状態で維持することで出生時ネフロン数を決定する [PDF]

, 2014
京都大学0048新制・課程博士博士(医学)甲第18503号医博第3923号新制||医||1005(附属図書館)31389京都大学大学院医学研究科医学専攻(主査)教授 山下 潤, 教授 斎藤 通紀, 教授 小川 修学位規則第4条第1項該当Doctor of Medical ScienceKyoto ...
Tomita, Mayumi
core   +1 more source

Advances and Prospects of Stereotactic Radiosurgery and Stereotactic Ablative Body Radiotherapy: Evolving Paradigms in Precision Oncology

Med Research, EarlyView.
The graphical abstract outlines the progressive development and impact of stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT). Technological Evolution illustrates the transition from brachytherapy with single‐dose, LDR/HDR schedules to fractionated radiotherapy, three‐dimensional conformal radiotherapy (3DCRT) and Gamma Knife ...
Jing Zhang, Wenhao Xu, Weiqing Lu, Yingxuan Lin, Luoxi He, Zonglin Lv, Yiliyaer Nuerrula, Zouting, Zhen Zhang, Hailiang Zhang, Xuejun Ma   +10 more
wiley   +1 more source

Bifurcation study of blood flow control in the kidney. [PDF]

, 2015
Renal blood flow is maintained within a narrow window by a set of intrinsic autoregulatory mechanisms. Here, a mathematical model of renal hemodynamics control in the rat kidney is used to understand the interactions between two major renal ...
Arciero, Julia C., Ellwein, Laura, Ford Versypt, Ashlee N., Layton, Anita T., Makrides, Elizabeth   +4 more
core   +1 more source

Gene expression profiles in developing nephrons using Lim1 metanephric mesenchyme-specific conditional mutant mice

BMC Nephrology, 2006
BackgroundLim1 is a homeobox gene that is essential for nephrogenesis. During metanephric kidney development, Lim1 is expressed in the nephric duct, ureteric buds, and the induced metanephric mesenchyme.
You‐Tzung Chen, Akio Kobayashi, K. Kwan, Randy L. Johnson, R. Behringer   +4 more
semanticscholar   +1 more source