Results 111 to 120 of about 50,163 (289)

Effects of high salt load on renal Hemodynamics and function in Normotension and hypertension: role of Alpha 1-adrenoceptor. [PDF]

, 2011
Hipertensi merupakan penyebab utama morbiditi dan kematian yang berkait rapat dengan penyakit jantung koroner, kegagalan ginjal dan strok. Natrium memainkan peranan patofisiologi yang penting di dalam pembentukkan hipertensi.
Kazi, Raisa Nazir Ahmed
core  

Detection of renal tubular transporter proteins in canine urinary extracellular vesicles using liquid chromatography–tandem mass spectrometry

Veterinary Clinical Pathology, EarlyView.
Abstract Urinary extracellular vesicles (UEVs) are membranous particles that carry renal tubular transporter proteins. Here, we evaluate whether selected renal tubular transporter proteins can be detected in UEVs isolated from small volume (1–5 mL) canine urine samples of healthy dogs and canine patients with elevated circulating parathyroid hormone ...
L. J. McGravey, P. R. Antrobus, T. L. Williams   +2 more
wiley   +1 more source

Impact of diet and exercise in growth restricted female rats on nephron endowment in male fetuses

Experimental Physiology, EarlyView.
Abstract Uteroplacental insufficiency impairs kidney development and programs male‐onset cardiorenal disease, which can be transmitted to subsequent generations. Maternal lifestyle factors can independently influence fetal kidney development, highlighting that the lifestyle of growth‐restricted females can have further influence on F2 kidney ...
Jessica F. Briffa, Sogand Gravina, Viktoria F. Richter, Dayana Mahizir, Kristina Anevska, Yeukai T. M. Mangwiro, James S. M. Cuffe, Fadi Charchar, Glenn D. Wadley, Deanne H. Hryciw, Karen M. Moritz, Mary E. Wlodek   +11 more
wiley   +1 more source

Ouabain‐induced hypertension in rats: Mechanisms, variability and translational implications

Experimental Physiology, EarlyView.
Abstract Ouabain‐induced hypertension is a multifactorial and condition‐dependent phenomenon involving coordinated actions across vascular, renal and central nervous system pathways. At the vascular level, ouabain inhibits Na⁺/K⁺‐ATPase, particularly the α2‐isoform, leading to elevated intracellular Ca2⁺, enhanced vasoconstriction and structural ...
Priscilla Rodrigues O. Feijó, Luis Eduardo M. Quintas   +1 more
wiley   +1 more source

NEPHRON NUMBER IN THE OFFSPRING OF RATS FED A LOW PROTEIN DIET DURING PREGNANCY

Image Analysis and Stereology, 2011
In experimental studies it has been shown that intrauterine growth retardation and reduced kidney growth during development are associated with significant decreases in nephron endowment.
Monika A Zimanyi, John F Bertram, Jane M Black   +2 more
doaj   +1 more source

One day of environment‐induced heat stress causes injury to the murine kidney

Experimental Physiology, EarlyView.
Abstract Environment‐induced heat stress (EIHS) results from sustained body temperature elevation owing to prolonged exposure to heat and humidity. We hypothesized that EIHS would cause kidney injury and cellular dysfunction. To test this hypothesis, female C57 mice were exposed to EIHS (n = 14; 37.6°C, 42.0% relative humidity) or thermoneutral (TN ...
Melissa Roths, Alyona Michael, Zachary J. Schlader, Joshua T. Selsby   +3 more
wiley   +1 more source

Selective In Vitro Propagation of Nephron Progenitors Derived from Embryos and Pluripotent Stem Cells

Cell Reports, 2016
Nephron progenitors in the embryonic kidney propagate while generating differentiated nephrons. However, in mice, the progenitors terminally differentiate shortly after birth.
Shunsuke Tanigawa, Atsuhiro Taguchi, Nirmala Sharma, Alan O. Perantoni, Ryuichi Nishinakamura   +4 more
doaj   +1 more source

Role of FGFRL1 and other FGF signaling proteins in early kidney development [PDF]

, 2018
The mammalian kidney develops from the ureteric bud and the metanephric mesenchyme. In mice, the ureteric bud invades the metanephric mesenchyme at day E10.5 and begins to branch. The tips of the ureteric bud induce the metanephric mesenchyme to condense
Amann, Ruth, Gerber, Simon, Trueb, Beat
core  

Cellular microenvironment of erythropoietin‐producing cells in hypoxic and injured mouse kidneys

Experimental Physiology, EarlyView.
Abstract The main sources of circulating erythropoietin (Epo) in the adult are kidney Norn cells, a recently identified interstitial cell type capable of becoming renal Epo‐producing (REP) cells following a local decrease in tissue oxygenation. REP cells are restricted to small clusters in the corticomedullary border region, suggesting that their ...
Olga M. Lempke, Thomas Knöpfel, Stellor Nlandu Khodo, Roland H. Wenger   +3 more
wiley   +1 more source

First In Vivo 23Na Human Imaging at 10.5 T Using a Combined Sodium‐Proton Transceiver Body Array

Magnetic Resonance in Medicine, Volume 95, Issue 4, Page 2429-2441, April 2026.
ABSTRACT Purpose To demonstrate the first in vivo human 23Na MRI at 10.5 T using a novel dual‐tuned transceiver body array and to evaluate a self‐gating approach for respiratory motion compensation, focusing on renal imaging. Methods A custom‐built eight‐channel 23Na‐loop 1H‐dipole transceiver array was designed, constructed, and characterized.
Simon Schmidt, Arcan M. Ertürk, Gregory J. Metzger   +2 more
wiley   +1 more source