Results 11 to 20 of about 50,163 (289)

Quantitative analysis of the nephron during human fetal kidney development [PDF]

open access: yesVojnosanitetski Pregled, 2005
Background. The development of human kidney is a complex process. The number, shape, size, and distribution of nephrons as functional units in a kidney, provide some important information about the organization of the kidney. The aim of this study was to
Daković-Bjelaković Marija Z.   +5 more
doaj   +1 more source

Long-term viable chimeric nephrons generated from progenitor cells are a reliable model in cisplatin-induced toxicity

open access: yesCommunications Biology, 2023
Kidney organoids have shown promise as evaluation tools, but their in vitro maturity remains limited. Transplantation into adult mice has aided in maturation; however, their lack of urinary tract connection limits long-term viability.
Kenji Matsui   +13 more
doaj   +1 more source

Evaluation of the nephrons number in children with congenital pathology of the cardiovascular system

open access: yesИзвестия высших учебных заведений. Поволжский регион: Медицинские науки, 2023
Background. The purpose of the study is to determine the dynamics of growth and differentiation of cortical and perimedullary nephrons in children with pathology of the cardiovascular system. Materials and methods.
A.A. Sologub   +3 more
doaj   +1 more source

In vivo regeneration of neo-nephrons in rodents by renal progenitor cell transplantation

open access: yesSTAR Protocols, 2021
Summary: Renal progenitor cells induced from pluripotent stem cells have attracted attention as a cell source for organ regeneration. Here, we report an in vivo protocol for the regeneration of urine-producing nephrons, i.e., neo-nephrons, in mice.
Shuichiro Yamanaka   +8 more
doaj   +1 more source

Adaptive changes in GFR, tubular morphology, and transport in subtotal nephrectomized kidneys: modeling and analysis [PDF]

open access: yes, 2017
Removal of renal mass stimulates anatomical and functional adaptations in the surviving nephrons, including elevations in single-nephron glomerular filtration rate (SNGFR) and tubular hypertrophy. A goal of this study is to assess the extent to which the
Edwards, Aurelie   +2 more
core   +1 more source

Direct physical contact between intercalated cells in the distal convoluted tubule and the afferent arteriole in mouse kidneys. [PDF]

open access: yesPLoS ONE, 2013
Recent physiological studies in the kidney proposed the existence of a secondary feedback mechanism termed 'crosstalk' localized after the macula densa. This newly discovered crosstalk contact between the nephron tubule and its own afferent arteriole may
Hao Ren   +6 more
doaj   +1 more source

Afadin orients cell division to position the tubule lumen in developing renal tubules [PDF]

open access: yes, 2017
In many types of tubules, continuity of the lumen is paramount to tubular function, yet how tubules generate lumen continuity in vivo is not known. We recently found the F-actin binding protein Afadin is required for lumen continuity in developing renal ...
Brakeman, Paul R.   +9 more
core   +2 more sources

Nephron induction [PDF]

open access: yesNephrology Dialysis Transplantation, 2002
One of the most remarkable transformations of cells during organogenesis is the epithelial transformation of nephrogenic mesenchyme to secretory nephrons. During recent years, gene targeting and organ culture approaches have been used efficiently to resolve key molecules involved in this multistage process.
openaire   +2 more sources

Quantitative morphology of renal cortical structures during compensatory hypertrophy [PDF]

open access: yes, 1998
The compensatory hypertrophy in different renal cortical structures was studied in rats 10 and 21 days after unilateral nephrectomy (UNX). Quantitative morphological/stereological analysis revealed significant increases in total renal cortical volume ...
Beck, Franz-X.   +4 more
core   +1 more source

Nephron-Sparing Surgery [PDF]

open access: yesSeminars in Interventional Radiology, 2014
Renal cell carcinoma (RCC) is a common malignancy with an increasing incidence.1 2 The classic triad of abdominal mass, hematuria, and flank pain accompanied by the various associated paraneoplastic syndromes (or the “internist's tumor”) are rare presentations of contemporary kidney cancer. With the current use and practice of modern abdominal imaging,
Paul, Maroni, Jacob, Moss
openaire   +2 more sources

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