Blood pressure and indices of glomerular filtration area in hypertensive and normotensive Prague rats [PDF]
, 2000 The involvement of the kidney in the pathogenesis of hypertension has long been recognised, although the specific renal mechanisms underlying this phenomenon are still unknown.
Davis, J. M., Hellmann, H., Thurau, K.
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Effects of renal pelvic high-pressure perfusion on nephrons in a porcine pyonephrosis model
Experimental and Therapeutic Medicine, 2013 The aim of this study was to investigate the effects of various renal pelvic pressure gradients on nephrons with purulent infection. Five miniature test pigs were selected.
Jian Wang +6 more
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A rare cause of recurrent spontaneous pneumothorax: Birt-hogg-dube syndrome [PDF]
, 2018 Birt-Hogg-Dube (BHD) syndrome is an unusual disorder characterized by the triad of cutaneous lesions, renal tumors and lung cysts. In cases with BHD syndrome, the frequency of recurrent pneumothorax is increased due to presence of multiple lung cysts. It
Demirci, M. +3 more
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Large-scale engineering of hiPSC-derived nephron sheets and cryopreservation of their progenitors
Stem Cell Research & Therapy, 2022 Background The generation of human induced pluripotent stem cells (hiPSCs) has opened a world of opportunities for stem cell-based therapies in regenerative medicine.
Loes E. Wiersma +4 more
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Nephrons require Rho-kinase for proximal-distal polarity development
Scientific Reports, 2013 Epithelial tubules must have the right length and pattern for proper function. In the nephron, planar cell polarity controls elongation along the proximal-distal axis.
N. Lindström, P. Hohenstein, J. Davies
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Nature Communications, 2022 While pluripotent stem cell-derived kidney organoids are now being used to model renal disease, the proximal nephron remains immature with limited evidence for key functional solute channels.
Jessica M. Vanslambrouck +11 more
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Brazilian Journal of NephrologyIt is interesting that some of my predictions came true and some did not, but I think the jury is still out on many of them. I start to remind everyone on the glorious past of Nephrology, from the physiology, translational and methodological discoveries ...
Richard Glassock
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Immunohistochemical Expression of TGF-β1 in Kidneys of Cats with Chronic Kidney Disease
Veterinary Sciences, 2022 Transforming growth factor-beta 1 (TGF-β1) plays a central role in the progression of chronic kidney disease (CKD). However, in feline CKD, renal expression of TGF-β1 and how it changes as the disease progresses have not been fully studied.
Yuki Uehara +6 more
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The Fate of Nephrons in Congenital Obstructive Nephropathy: Adult Recovery is Limited by Nephron Number Despite Early Release of Obstruction [PDF]
, 2015 Urinary tract obstruction and reduced nephron number often occur together as a result of maldevelopment of kidneys and urinary tract. We wished to determine the role of nephron number on the adaptation of remaining nephrons of mice subjected to neonatal ...
Chevalier, R. +4 more
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Understanding Kidney Health: Physiology, Diagnostic Markers, and Pathological Conditions
Biobacta Journal of Biochemistry and Molecular BiologyThe kidney is a vital organ responsible for several essential functions, including waste elimination, fluid and electrolyte balance, blood pressure regulation, and hormone production.
Kenz Yameny
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