Results 61 to 70 of about 3,794 (116)

Renoprotective Effects of Melatonin in Young Spontaneously Hypertensive Rats with L-NAME

Pediatrics and Neonatology, 2014
Nitric oxide (NO) deficiency occurs in humans and animals with hypertension and chronic kidney disease (CKD). An inhibitor of NO synthase, NG-nitro-l-arginine methyl ester (L-NAME) exacerbates kidney damage in the adult spontaneously hypertensive rat ...
Ming-Chou Cheng, Ting-Hsin Wu, Li-Tung Huang, You-Lin Tain   +3 more
doaj   +1 more source

Prediction of decreased estimated glomerular filtration rate using liver fibrosis markers: a renal biopsy-based study

Scientific Reports, 2022
Non-alcoholic fatty liver disease is the most common chronic liver disease and is associated with chronic kidney disease. The fibrosis-4 index and non-alcoholic fatty liver disease score are widely used as non-invasive diagnostic methods for non ...
Akira Mima
doaj   +1 more source

MXRA5 is a TGF-β1-regulated human protein with anti-inflammatory and anti-fibrotic properties [PDF]

, 2017
Current therapy for chronic kidney disease (CKD) is unsatisfactory because of an insufficient understanding of its pathogenesis. Matrix remodelling-associated protein 5 (MXRA5, adlican) is a human protein of unknown function with high kidney tissue ...
Carrasco, Susana, Fernández-Fernández, Beatriz, Poveda, Jonay, Ruiz-Ortega, Marta, Sanz, Ana Belén   +4 more
core   +2 more sources

Incidents of sudden death during restraint of agitated individuals in Sweden between 1992 and 2024

Journal of Forensic Sciences, Volume 71, Issue 2, Page 821-836, March 2026.
Abstract Restraint‐related sudden deaths in agitated individuals raise complex questions at the intersection of medicine and law. Hyperactive delirium with extreme agitation as well as positional asphyxia due to restraint have been proposed to account for these deaths. However, the exact physiological mechanisms responsible and to what extent restraint
Alexander Tyr, Erik Lindeman, Fredrik Tamsen, Ingemar Thiblin, Brita Zilg   +4 more
wiley   +1 more source

Literature‐informed ensemble machine learning for three‐year diabetic kidney disease risk prediction in type 2 diabetes: Development, validation, and deployment of the PSMMC NephraRisk model

Diabetes, Obesity and Metabolism, Volume 28, Issue 3, Page 1997-2026, March 2026.
Abstract Introduction Diabetic kidney disease (DKD) and diabetic nephropathy (DN) affect around 40% of diabetic patients but lack accurate risk prediction tools that include social determinants and demographic complexity. We developed and validated an ensemble machine learning model for three‐year DKD/DN risk prediction with deployment readiness ...
Ayla M. Tourkmani, Turki J. Al‐Harbi, Ahmad Abdullah Alghamdi, Ibrahim M. Youzghadli, Faris Saad Alosaimi, Ahmed Y. Azzam   +5 more
wiley   +1 more source

Peritoneal defense in continuous ambulatory versus continuous cyclic peritoneal dialysis [PDF]

, 1992
Peritoneal defense in continuous ambulatory peritoneal dialysis versus continuous cyclic peritoneal dialysis. Several centers have reported a lower rate of peritonitis among adult patients on continuous cyclic peritoneal dialysis (CCPD) as compared to ...
de Fijter, Carola W.H., Verbrugh, Henri A., Oe, Liem P., Peters, Edith D.J., van der Meulen, Jan, Donker, Ab J.M., Verhoef, Jan   +6 more
core   +11 more sources

Primary and Secondary Grzybowski’s Generalized Eruptive Keratoacanthoma: A New Perspective on Management, Clinical Features, and Prognosis

International Journal of Dermatology, Volume 65, Issue 3, Page 456-463, March 2026.
ABSTRACT Grzybowski's generalized eruptive keratoacanthoma (GEKA) is a rare variant of keratoacanthomas, characterized by hundreds to thousands of lesions, accompanied by pruritus, mucosal involvement, and comorbidities. Our aim was to analyze the clinical presentation, associated comorbidities, treatment strategies, and outcomes of GEKA.
Nicholas Florin Kormos, Carina Maria Petrenciu, Alin Stefan Vizitiu, Raluca Ghețe, Umer Nadir, Adrian Lucian Baican, Stanislav N. Tolkachjov   +6 more
wiley   +1 more source

Molecular factors of angiogenesis in renal tissue of patients with chronic glomerulonephritis: association with nephrosclerosis and anemia

Терапевтический архив, 2009
Aim. To study correlations between accumulation of angiogenesis molecular factors (hypoxia-inducible factor-1alpha - HIF-1α, vascular endothelial growth factor - VEGF, thrombospondin -TSP-1) in kidney biopsy tissue from chronic glomerulonephritis (CGN ...
Mikhail Yur'evich Shvetsov, Aleksey Alekseevich Ivanov, Alla Viktorovna Kuznetsova, Ol'ga Petrovna Popova, Anna Sergeevna Rameeva, M Yu Shvetsov, A A Ivanov, A V Kuznetsova, O P Popova, A S Rameeva   +9 more
doaj  

Construction of a prognostic assessment model for diabetic nephropathy based on serum fibrinogen and renal tissue IFTA score

Journal of Diabetes Investigation, Volume 17, Issue 3, Page 448-459, March 2026.
ABSTRACT Objective To explore the association between serum fibrinogen (FIB) and clinicopathological features and renal prognosis in type 2 diabetic nephropathy (T2DN), and develop a web‐based dynamic model to predict renal progression. Methods This paper retrospectively enrolled 173 biopsy‐proven T2DN patients and stratified them by the optimal FIB ...
Lin Ning, Xiaohong Zhang, Yuan Fang, Mengjie Weng, Yongjie Zhuo, Jianxin Wan   +5 more
wiley   +1 more source

Long-term functioning of kidney grafts

Сучасні медичні технології, 2020
Purpose of the study. to study the morphological changes of long-functioning kidney transplants and determine the main causes of transplant dysfunction. Materials and methods.
T. N. Nikonenko, A. V. Trailin, V. N. Nepomnyashchy, S. V. Fen, S. R. Vildanov, I. R. Rusanov, A. S. Nikonenko   +6 more
doaj   +1 more source