Results 261 to 270 of about 26,327 (353)

Neprilysin 2 catalyses the degradation of natriuretic peptides despite sacubitrilat Inhibition. [PDF]

Sci Rep
Selezneva EM, Feygina EE, Ageeva LV, Rozov FN, Kopylova IV, Altshuler EP, Semenov AG.   +6 more
europepmc   +1 more source

Decoding Glycosylation in Neurodegenerative Diseases: Mechanistic Insights and Therapeutic Opportunities

The FASEB Journal, Volume 39, Issue 20, 31 October 2025.
Graphical summary of glycosylation impairments in various neurodegenerative disorders. Among the diverse forms of glycosylation, the most extensively studied include N‐glycosylation, O‐glycosylation, and O‐GlcNAcylation. Aberrant glycosylation has been implicated in multiple neurodegenerative conditions.
Haihan Yu, Xing Chen, Yang Yang, Mengke Gu, Kaidi Ren, Ziqing Wei   +5 more
wiley   +1 more source

Assessment of Risk Factors for Vasoplegic Syndrome in Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass. [PDF]

Cureus
Meyer KA, Brink HL, Brannan SC, Lundgren SW, Lyden ER, Behlers QB.   +5 more
europepmc   +1 more source

Glymphatic and meningeal lymphatic dysfunction in Alzheimer's disease: Mechanisms and therapeutic perspectives

Alzheimer's &Dementia, Volume 21, Issue 10, October 2025.
Abstract Alzheimer's disease (AD) is a neurodegenerative disorder characterized by amyloid‐beta (Aβ) deposition and tau pathology. Although disease‐modifying therapies, such as anti‐Aβ monoclonal antibodies, have been approved, their clinical efficacy remains modest and accompanied by substantial safety concerns. The glymphatic system, which is a brain‐
Jiangwei Ding, Chengbin Zhao, Xiaoyan Hao, Hongliang Jiao   +3 more
wiley   +1 more source

Therapeutic potential of hUC-MSC secretome preconditioned with IFN-γ and/or TNF-α: An in vitro study on Alzheimer's neuronal cell models. [PDF]

Narra J
Widaja E, Pawitan JA, Ramli Y.
europepmc   +1 more source

Neuropeptide Levels as well as Neprilysin Activity Decrease in Renal Cell Carcinoma

, 2016
Nuray Erin, Tümay İpekçi, Bahar Akkaya, İrem Hicran Özbudak, Mehmet Baykara   +4 more
openalex   +2 more sources

Potential of ECW/ICW and ECW/TBW as Early and Sensitive Indicators of Chronic Heart Failure Status and Medication Adherence in a Patient With Dementia: A Case Report

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT In an elderly patient with chronic heart failure (CHF) and dementia, the extracellular fluid volume (ECW)/intracellular fluid volume (ICW) and ECW/total body water (TBW) ratios measured by bioelectrical impedance analysis (BIA) may serve as early and sensitive indicators of CHF status and effective markers for assessing medication adherence.
Junko Shida, Hiromi Misawa, Tomomi Suzuki, Nozomi Aoki, Mai Miura, Itsuro Kazama, Masahiro Wanezaki, Ryosuke Watanabe, Chisaki Uno, Yumi Matsuda   +9 more
wiley   +1 more source

New Fuels for a Failing Engine: The Impact of Novel Heart Failure Drugs on Functional Capacity. [PDF]

Rev Cardiovasc Med
Baracchini N, Capovilla TM, Costantino S, Puttini F, Salvioni E, Mattavelli I, Valenti M, d'Elia E, Bertarelli E, Agostoni P, Sinagra G, Mapelli M.   +11 more
europepmc   +1 more source

The use of echocardiography and echocardiographic findings in patients hospitalized for acute heart failure

ESC Heart Failure, Volume 12, Issue 5, Page 3678-3687, October 2025.
Abstract Aims Transthoracic echocardiography (TTE) is recommended as a key investigation in patients with acute heart failure (AHF) in major guidelines. However, utilization and benefits are yet to be known in Thai patients. The study aims to evaluate the benefits of TTE and identify factors associated with the decision to perform TTE on patients with ...
Koravich Lorlowhakarn, Thanaporn Ratchataswan, Thiratest Leesutipornchai, Aunchalee Jaroenlapnopparat, Palapun Waitayangkoon, Supanee Sinphurmsukskul, Sarawut Siwamogsatham, Sarinya Puwanant, Smonporn Boonyaratavej Songmuang, Aekarach Ariyachaipanich   +9 more
wiley   +1 more source

Sacubitril/Valsartan attenuates progression of diabetic cardiomyopathy through immunomodulation properties: an opportunity to prevent progressive disease. [PDF]

Cardiovasc Diabetol
Karuna N, Kerrigan L, Edgar K, Ledwidge M, McDonald K, Grieve DJ, Watson CJ.   +6 more
europepmc   +1 more source