Results 271 to 280 of about 25,082 (343)

The heart regulates the endocrine response to heart failure: cardiac contribution to circulating neprilysin

, 2017
Mattia Arrigo, Nicolas Vodovar, Hélène Nougue, Malha Sadoune, Chris Frampton, P Ballan, Pierre‐Olivier Ludes, Nicolas Gendron, Alain Carpentier, Bernard Cholley, Philippe Bizouarn, Alain Cohen‐Solal, Jagmeet P. Singh, Jackie Szymonifka, Christian Latrémouille, Jane‐Lise Samuel, Jean‐Marie Launay, Julien Pottecher, Mark Richards, Quynh A. Truong, David M. Smadja, Alexandre Mebazaa   +21 more
openalex   +1 more source

Surface Engineering‐Induced d‐Band Center Down‐Regulation in High‐Entropy Alloy Nanowires for Enhanced Nanozyme Catalysis

Advanced Science, Volume 12, Issue 25, July 3, 2025.
PtRuFeCoNi HEA NWs are synthesized by adjusting the metal composition and surface‐engineered with PDA to create HEA NWs@PDA nanozymes with superior catalytic activities and photothermal properties. DFT calculations confirm that self‐polymerized PDA surface engineering moderately lowers the d‐band center of the HEAs, optimizes the surface charge ...
Kunyang Feng, Hanting Wang, Song Zhou, Wei Zhang, Chonghai Gong, Yuxin He, Yusen Wang, Wenchong Dai, Jianbo Li, Zhengwei Zhang, Siqiao Li   +10 more
wiley   +1 more source

RARE CODING VARIANTS IN THE MME GENE, ENCODING THE METALLOPROTEASE NEPRILYSIN, ARE LINKED TO LATE-ONSET AXONAL NEUROPATHIES [PDF]

, 2016
Michaela Auer‐Grumbach, David Bennett, Peter M. Andersen, Matthew B. Harms, Mary M. Reilly, Jochen H. Weishaupt, Tim M. Strom, Tatjana Walther, S. S. Scherer, Stephan Züchner, Rina Martini, Jan Senderek   +11 more
openalex  

Synbiotics of Lactobacillus suilingensis and inulin alleviates cognitive impairment via regulating gut microbiota indole‐3‐lactic acid metabolism in female AD mice

Alzheimer's &Dementia, Volume 21, Issue 7, July 2025.
Abstract INTRODUCTION Recent studies have found that gut microbial tryptophan metabolism is altered in Alzheimer's disease (AD) patients. However, the functional consequences of these changes and their therapeutic potential remain unclear. METHODS The metagenomic data of 49 preclinical AD patients and 115 healthy controls were analyzed.
Cong Yang, Jingxi Sun, Ling Li, Jin Zheng, Chuhan Wang, Yu Zhao, Duo Yun, Mengzhen Jia, Zhinan Wu, Hewei Liang, Wenxi Li, Tongyuan Hu, Rui Guo, Liang Xiao, Yuanqiang Zou, Zhigang Liu   +15 more
wiley   +1 more source

Novel Versus Conventional Sequencing of β-Blockers, Sodium/Glucose Cotransportor 2 Inhibitors, Angiotensin Receptor-Neprilysin Inhibitors, and Mineralocorticoid Receptor Antagonists in Stable Patients With Heart Failure With Reduced Ejection Fraction (NovCon Sequencing Study): Protocol for a Randomized Controlled Trial.

JMIR Res Protoc
Karamchand S, Chipamaunga T, Naidoo P, Naidoo K, Rambiritch V, Ho K, Chilton R, McMahon K, Leisegang R, Weich H, Hassan K.   +10 more
europepmc   +1 more source

Sacubitril/Valsartan vs ACE Inhibitors or ARBs: A Systematic Review and Meta-Analysis of Randomized Trials. [PDF]

JACC Adv
Evbayekha E, Idowu AB, LaRue S.
europepmc   +1 more source

Real Time Hemodynamic Monitoring During M‐TEER Using Electrical Cardiometry

Catheterization and Cardiovascular Interventions, Volume 106, Issue 1, Page 196-202, July 1, 2025.
ABSTRACT Background Mitral regurgitation is a common valvular dysfunction causing patient morbidity and mortality. Mitral transcatheter edge‐to‐edge repair (M‐TEER) allows grasping of valvular leaflets and approximation via a small implant, thus reducing mitral regurgitation (MR).
Andreas Goldschmied, Manuel Sigle, Ioannis Toskas, Monika Zdanyte, Mareike Bladt, Meinrad Gawaz, Tobias Geisler   +6 more
wiley   +1 more source

Association of Circulating Neprilysin with BMI, Cardiovascular Health, and Kidney Function in High-Risk Pregnancies: A Pilot Study. [PDF]

Biomedicines
Hasani KK, Kulovic-Sissawo A, Saloň A, Stern C, Mayer-Pickel K, Cervar-Zivkovic M, Goswami N, Fluhr H, Hiden U.   +8 more
europepmc   +1 more source

Tolerability and Adverse Effects in a Specialized Heart Failure Guideline‐Directed Medical Therapy Optimization Program

Clinical Cardiology, Volume 48, Issue 7, July 2025.
ABSTRACT Background Utilization of heart failure (HF) guideline‐directed medical therapy (GDMT) to target doses is suboptimal, with studies citing adverse effects (AEs), physiological factors, and therapeutic inertia as potential contributing factors.
Claudia Mae Velasco, Gladys Baksh, Michele Haydo, Heather Reesor, John Boehmer, Omaima Ali   +5 more
wiley   +1 more source

Implications of Oxidative Stress in the Pathophysiological Pathways of Heart Failure. [PDF]

Int J Mol Sci
D'Amato A, Cestiè C, Ferranti F, Segato C, Prosperi S, Germanò R, Myftari V, Bartimoccia S, Castellani V, Badagliacca R, Cammisotto V, Pignatelli P, Vizza CD, Severino P.   +13 more
europepmc   +1 more source