Results 271 to 280 of about 26,327 (353)

Improvements in medical therapy and prognosis for patients with HFrEF following the 2021 ESC HF guidelines

ESC Heart Failure, Volume 12, Issue 5, Page 3343-3352, October 2025.
Abstract Aims The guideline‐directed medical therapy (GDMT) sequencing strategy for patients with heart failure (HF) and reduced ejection fraction (HFrEF) underwent a paradigm shift with the 2021 ESC HF guidelines, from stepwise escalation to rapid simultaneous initiation of quadruple therapy.
Kristian Berge, Henrik Schirmer, Tarjei Øvrebotten, Hamza Nahoui, Lars Gullestad, Charlotte Björk Ingul, Torstein Hole, Rune Mo, Kristina Larsby, Tone M. Norekvål, Torbjørn Omland, Stein Ørn, Peder L. Myhre   +12 more
wiley   +1 more source

Hyperkalemia in Heart Failure with Reduced Ejection Fraction Patients Treated with Sacubitril/Valsartan: Experience from a Tertiary Cardiac Center in Riyadh, Saudi Arabia. [PDF]

Clin Pract
Alyousif SM, Alaqil NK, Abdelshafy M, Alasmari T, Alqadhy NH, Alzahrani NS, Alhefdhi MA, Alqahtani NA, Omair A, Alsaileek A.   +9 more
europepmc   +1 more source

Renal Sympathetic Denervation Protects the Failing Heart Via Inhibition of Neprilysin Activity in the Kidney

, 2017
David J. Polhemus, Rishi Trivedi, Juan Gao, Zhen Li, Amy Scarborough, Traci Goodchild, Kurt J. Varner, Huijing Xia, Frank W. Smart, Daniel R. Kapusta, David J. Lefer   +10 more
openalex   +1 more source

Implementation of guidelines for intravenous iron therapy in heart failure patients

ESC Heart Failure, Volume 12, Issue 5, Page 3475-3482, October 2025.
Abstract Aims We aim to evaluate the implementation of the 2021 ESC Guidelines regarding screening and treatment of iron deficiency in patients with heart failure (HF) at Karolinska University Hospital. Methods and results Patients with left ventricular ejection fraction (LVEF) < 50% and New York Heart Association (NYHA) class II–IV who visited ...
Milou Gamage, Aristomenis Manouras, Camilla Hage, Gianluigi Savarese, Karin Ljung, Michael Melin   +5 more
wiley   +1 more source

Decreased Endothelin-1 bioavailability impairs aggressiveness of gallbladder cancer cells. [PDF]

Biol Res
Vidal-Vidal J, Brown-Brown D, Quilaqueo-Millaqueo N, Peña-Münzenmayer G, Spichiger C, Quezada-Monrás C, Salazar-Onfray F, Tapia JC, Niechi I.   +8 more
europepmc   +1 more source

The heart regulates the endocrine response to heart failure: cardiac contribution to circulating neprilysin

, 2017
Mattia Arrigo, Nicolas Vodovar, Hélène Nougue, Malha Sadoune, Chris Frampton, P Ballan, Pierre‐Olivier Ludes, Nicolas Gendron, Alain Carpentier, Bernard Cholley, Philippe Bizouarn, Alain Cohen‐Solal, Jagmeet P. Singh, Jackie Szymonifka, Christian Latrémouille, Jane‐Lise Samuel, Jean‐Marie Launay, Julien Pottecher, Mark Richards, Quynh A. Truong, David M. Smadja, Alexandre Mebazaa   +21 more
openalex   +1 more source

Interconnected pathways and emerging therapies in chronic kidney disease and heart failure: A comprehensive review

ESC Heart Failure, Volume 12, Issue 5, Page 3226-3249, October 2025.
Abstract Chronic kidney disease (CKD) and chronic heart failure (HF) frequently coexist and, when comorbid, are associated with poorer outcomes. These two diseases have common risk factors, such as diabetes, obesity and hypertension, and common pathophysiological connected mechanisms, including inflammation, endothelial dysfunction, neurohormonal ...
Johann Bauersachs, Eri Toda Kato, Janani Rangaswami   +2 more
wiley   +1 more source

Cardiac Rehabilitation and Heart Failure With Preserved Ejection Fraction. [PDF]

Circ Rep
Hirashiki A, Shimizu A.
europepmc   +1 more source

Clinical impact of follow‐up endomyocardial biopsy in myocarditis during or after immune‐suppressive therapy

ESC Heart Failure, Volume 12, Issue 5, Page 3707-3718, October 2025.
Results and clinical implication of repeat endomyocardial biopsy (EMB). Abstract Aims While the diagnostic role of endomyocardial biopsy (EMB) in myocarditis is unquestioned, little is known about its indications and clinical value during long‐term follow‐up.
Anna Baritussio, Andrea Silvio Giordani, Stefania Rizzo, Cristina Vicenzetto, Monica De Gaspari, Elisa Carturan, Giuseppe Toscano, Federico Scognamiglio, Giuseppe Tarantini, Sabino Iliceto, Cristina Basso, Renzo Marcolongo, Alida Linda Patrizia Caforio   +12 more
wiley   +1 more source

Pharmacist-led guideline-directed medical therapy in heart failure: impact analysis in primary care. [PDF]

BMJ Open Qual
Schichtel M, Barclay S, Papworth H, Mills L, Bowers B.   +4 more
europepmc   +1 more source