Highly efficient manipulation of nervous system gene expression with NEPTUNE
Summary: Genetic loss and gain of function in mice have typically been studied by using knockout or knockin mice that take months to years to generate.
Katrin Mangold +5 more
doaj +1 more source
Eculizumab as a Treatment for Hyper-Haemolytic and Aplastic Crisis in Sickle Cell Disease
Background: Patients with sickle cell disease can experience various crises including sequestration crisis, haemolytic crisis and aplastic crisis. Due to alloantibody formation, transfusion alloantibodies can cause a haemolytic crisis. Treatment involves
Ishan Patel +7 more
doaj +1 more source
Health Inequities in Pediatric Trauma
This review article highlights the disparities evident in pediatric trauma care in the United States. Social determinants of health play a significant role in key aspects of trauma care including access to care, gun violence, child abuse, head trauma ...
Mark L. Kayton +7 more
doaj +1 more source
Endoleaks are a common complication of endovascular aortic aneurysm repair and often lead to aneurysm rupture. We report a complex case of a Type IIIA endoleak in a patient with suspected cholangitis.
Emmanuel Ihionkhan +4 more
doaj +1 more source
MOA-2010-BLG-328Lb: a sub-Neptune orbiting very late M dwarf ? [PDF]
peer reviewedWe analyze the planetary microlensing event MOA-2010-BLG-328. The best fit yields host and planetary masses of Mh = 0.11+/-0.01 M_{sun} and Mp = 9.2+/-2.2M_Earth, corresponding to a very late M dwarf and sub-Neptune-mass planet, respectively.
Southworth, J. +709 more
core +2 more sources
Pressure‐Induced sp 2 ‐sp 3 Transitions in Carbon‐Bearing Phases
This book is Open Access. A digital copy can be downloaded for free from Wiley Online Library.
Explores the behavior of carbon in minerals, melts, and fluids under extreme conditions
Carbon trapped in diamonds and carbonate-bearing rocks in subduction zones are examples of the continuing exchange of substantial carbon ...
Sergey S. Lobanov +1 more
wiley +1 more source
Background Hypertension is a global health issue associated with increased cardiovascular morbidity and mortality. This study aimed to investigate contemporary hypertension identification and management trends following the 2017 American College of ...
Joseph Heaton +7 more
doaj +1 more source
We report an interesting case of a 2-year-old boy with congenital absence of the left external iliac vein and an anomalous lower extremity venous connection.
Robyn Guinto, MD +3 more
doaj +1 more source
Origin and dynamical evolution of Neptune Trojans - I. Formation and planetary migration [PDF]
We present the results of detailed dynamical simulations of the effect of the migration of the four giant planets on both the transport of pre-formed Neptune Trojans and the capture of new Trojans from a trans-Neptunian disc.
Mukai, T. +3 more
core +1 more source
Fabrication shapes soft robot performance, but benchmarking data and selection guidelines remain scarce. We fabricate silicone actuators using two molding techniques and three mold types, characterizing them with cycle testing, microscopy, profilometry, and 3D imaging. Applying our lab‐scale, soft robotics‐specific fabrication evaluation criteria shows
Charlotte M. Folinus +3 more
wiley +1 more source

