Amyloid proteotoxicity initiates an inflammatory response blocked by cannabinoids. [PDF]
The beta amyloid (Aβ) and other aggregating proteins in the brain increase with age and are frequently found within neurons. The mechanistic relationship between intracellular amyloid, aging and neurodegeneration is not, however, well understood.
Currais, Antonio +5 more
core +2 more sources
Current status of diagnosis and treatment of menopausal syndrome and the application of stellate ganglion block [PDF]
Menopausal syndrome has a high incidence rate and significantly impacts women’s physical and mental health. Its exact pathogenesis remains unclear, but it is generally believed that hormonal changes during menopause are the primary cause of multisystem ...
XING Jibin, LI Xiang, CHENG Nan, FANG Li, ZHOU Shaoli
doaj +1 more source
Postoperative Analgesia in Ultrasound-Guided 3-in-1 Block versus Fascia Illiaca Compartment Block in Adult Patients Undergoing Lower Limb Orthopaedic Surgeries under General Anaesthesia: A Randomised Clinical Study [PDF]
Introduction: Three-in-one block and Fascia Illiaca Compartment Block (FICB) are two peripheral nerve block techniques that target the femoral nerve, obturator nerve and lateral femoral cutaneous nerve in a single injection. Both nerve blocks are used to
S Keerthana +3 more
doaj +1 more source
Description of a new approach for great auricular and auriculotemporal nerve blocks: A cadaveric study in foxes and dogs [PDF]
Otitis externa is a painful condition that may require surgical intervention in dogs. A balanced analgesia protocol should combine systemic analgesic agents and local anaesthesia techniques.
Beckman +13 more
core +3 more sources
A pragmatic randomised controlled trial comparing the efficacy of a femoral nerve block and periarticular infiltration for early pain relief following total knee arthroplasty [PDF]
Aims The aim of this study was to compare the effectiveness of a femoral nerve block and a periarticular infiltration in the management of early post-operative pain after total knee arthroplasty (TKA).
Achten, Juul +7 more
core +2 more sources
PolyMorphine provides extended analgesic-like effects in mice with spared nerve injury. [PDF]
Morphine is a well-characterized and effective analgesic commonly used to provide pain relief to patients suffering from both acute and chronic pain conditions.
Chen, Renxun +5 more
core +1 more source
Ultrasound-Guided Lateral Femoral Cutaneous Nerve Cryoneurolysis for Analgesia in Patients With Burns. [PDF]
Autologous skin grafting from the thigh is frequently required for treatment of burns and is associated with intense pain at the donor site. Local anesthetic-based (LA) nerve blocks of the lateral femoral cutaneous nerve (LFCN) have been demonstrated to ...
Fiallo, Alfredo +6 more
core
Study objectiveTo quantitatively assess and compare the efficacy and adverse effects of six different peripheral nerve block techniques after arthroscopic shoulder surgery (ASS).DesignBayesian network meta-analysis.MethodsThe PubMed, Embase, Web of ...
Zheng Liu +4 more
doaj +1 more source
Blockade of the mental nerve for lower lip surgery as a safe alternative to general anesthesia in two very old patients [PDF]
Purpose: Regional anesthesia is gaining popularity with anesthesiologists as it offers superb postoperative analgesia. However, as the sole anesthetic technique in high-risk patients in whom general anesthesia is not preferred, some regional anesthetic ...
Reidinga, Auke C. +4 more
core +2 more sources
Femoral Nerve Block Intervention in Neck of Femur Fracture (FINOF): a randomized controlled trial [PDF]
Objective Fractured neck of femur is a severely painful condition with significant mortality and morbidity. We investigated whether early and continuous use of femoral nerve block can improve pain on movement and mobility after surgery in older ...
Armstrong, Sarah +7 more
core +2 more sources

