Results 121 to 130 of about 14,744 (303)

New insights into applications of base editor in hereditary disorders

open access: yesInterdisciplinary Medicine, EarlyView.
Abstract Hereditary disorders are a group of diseases caused by genetic mutations or chromosomal variations. Although the incidence of each genetic disorder is relatively low, patients affected by the disease generally experience a range of severe symptoms, including blindness, disability, and even premature death. In addition, the available treatments
Maoping Cai   +8 more
wiley   +1 more source

Dynamic Ultrasound Imaging of Extensor Pollicis Brevis Hypertrophy in Proximal Intersection Syndrome: A Case Report and Literature Review

open access: yesJournal of Clinical Ultrasound, EarlyView.
Dynamic ultrasound revealed extensor pollicis brevis hypertrophy displacing second compartment tendons, suggesting a novel friction‐based mechanism for proximal intersection syndrome. This case highlights the role of dynamic sonography in identifying motion‐dependent tendon interactions underlying overuse‐related wrist pain.
Daoukas Stavros   +3 more
wiley   +1 more source

Sonographic Anatomy and Imaging of the Extracranial Component of the Hypoglossal Nerve (CNXII)

open access: yesJournal of Medical Radiation Sciences, EarlyView.
The hypoglossal nerve (HN) provides motor innervation to tongue muscles responsible for tongue movement, speech, mastication, swallowing, respiratory functions and management of oral secretions. The intracranial component of the HN can be demonstrated on magnetic resonance imaging and the extracranial component can be demonstrated with sonographic ...
Michelle Fenech   +4 more
wiley   +1 more source

Overuse‐Induced Muscle Disorder: Establishing a Rat Model to Unravel the Role of Fibro‐Adipogenic Progenitor Cells in Intramuscular Fibrosis

open access: yesJournal of Orthopaedic Research, EarlyView.
ABSTRACT Overuse‐induced muscle disorders (OIMD) frequently occur in athletes due to excessive and improper use under high physical demand, often leading to muscle pain and weakness. Limited studies have shown intramuscular fibrosis in OIMD, with fibro‐adipogenic progenitors (FAPs), also known as mesenchymal stromal cells (MSCs), playing a crucial role
Hiroyori Fusagawa   +17 more
wiley   +1 more source

Pyridostigmine as treatment for chronic gastrointestinal dysmotility in a child with Mowat‐Wilson syndrome: A case report and literature review

open access: yesJPGN Reports, EarlyView.
Abstract Gastrointestinal dysmotility is commonly reported among patients with Mowat‐Wilson syndrome (MWS) and poses a significant symptomatic burden. Unfortunately, there remains a knowledge gap regarding effective treatment strategies. A 2‐year‐old male with MWS presented with chronic paradoxical abdominal pain, constipation, and progressively ...
Grace J. Lin   +5 more
wiley   +1 more source

Gastrointestinal malrotation and chronic intestinal pseudo‐obstruction in two pediatric patients with Baraitser‐Winter cerebrofrontofacial syndrome

open access: yesJPGN Reports, EarlyView.
Abstract Baraitser‐Winter cerebrofrontofacial syndrome (BWCFF) is a rare congenital anomaly syndrome that can present with characteristics in multiple organ systems. These can include pachygyria, intellectual disability, seizures, congenital heart defects, renal malformations and gastrointestinal dysfunction.
Veronica Lee   +4 more
wiley   +1 more source

High‐Resolution Ultrasound of Clinically Relevant Sensory Nerves of the Arm and the Forearm

open access: yesJournal of Ultrasound in Medicine, EarlyView.
Technological advancements in ultrasound systems, particularly the development of high‐ and ultra‐high‐frequency transducers, now allow for the detailed evaluation of sub‐millimetric sensory nerves in the upper limb, extending to their distal branches. This provides invaluable insights in patients with suspected neuropathies.
Federico Zaottini   +9 more
wiley   +1 more source

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