Results 271 to 280 of about 24,441 (347)

Early signs of cardiovascular abnormalities in patients with alcohol misuse

open access: yesAlcohol, Clinical and Experimental Research, EarlyView.
This study identifies cardiovascular patterns, such as mean arterial pressure, heart rate, and abnormal P‐wave axis on the ECG, present in a sample of alcohol drinkers. These biomarkers may help detect increasing and potentially harmful alcohol consumption in patients who do not yet meet the criteria for “high‐risk drinking” and could benefit from ...
Lisa A. Farinelli   +6 more
wiley   +1 more source

Naloxone dosing in the era of synthetic opioids: Applying the Goldilocks principle

open access: yesAddiction, EarlyView.
Abstract The opioid overdose epidemic remains a critical public health crisis. In recent years, synthetic opioids like fentanyl and nitazenes, have driven a sharp rise in deaths. Naloxone, an opioid receptor antagonist, has been established as a key intervention for reversing opioid overdoses and saving lives.
Mariana Gonzalez Utrilla   +8 more
wiley   +1 more source

Management of xylazine toxicity, overdose, dependence, and withdrawal: A systematic review

open access: yesThe American Journal on Addictions, EarlyView.
Abstract Background and Objectives Xylazine, an alpha‐2‐adrenergic agonist, has been increasingly implicated in substance use and overdose crises. However, little is known about its effects on humans. With the growing public health crisis surrounding xylazine, it has become important to recognize and promptly manage symptoms of xylazine toxicity ...
Philipa Owusu‐Antwi   +4 more
wiley   +1 more source

Survivorship Needs and Experiences of Survivors of Head and Neck Cancer in Rural Australia: A Qualitative Study

open access: yesAsia-Pacific Journal of Clinical Oncology, EarlyView.
Semi‐structured interviews with 17 rural head and neck cancer survivors revealed six main themes relating to their survivorship needs and experiences: 1) financial impacts, 2) physical effects, 3) psychosocial effects, 4) clinical management, 5) information and support needs, and 6) access.
Poorva Pradhan   +14 more
wiley   +1 more source

Hemifacial spasm: an update on pathophysiology, investigations and management. [PDF]

open access: yesJ Neurol
Jesuthasan A   +4 more
europepmc   +1 more source

Relaxin‐2 improves type I diabetes mellitus‐induced erectile dysfunction in rats by protecting cavernous endothelial and smooth muscle function, and inhibiting penile fibrosis and apoptosis

open access: yesAndrology, EarlyView.
Abstract Background Diabetes mellitus‐induced erectile dysfunction (DMED) responds poorly to first‐line treatments, necessitating the development of new therapeutic strategies. Relaxin‐2 (RLX‐2) plays a crucial role in protecting vascular endothelium, vasodilatation, and antifibrosis in various diseases.
Bocheng Tu   +10 more
wiley   +1 more source

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