Results 51 to 60 of about 1,142,709 (351)

Reversible median nerve impairment after three weeks of repetitive work

Scandinavian Journal of Work, Environment & Health, 2017
OBJECTIVES: The aim of this study was to evaluate the development of impaired median nerve function in relation to hand-intensive seasonal work. We hypothesized that at end-season, median nerve conduction would be impaired and then recover within weeks ...
Sorosh Tabatabaeifar, Susanne Wulff Svendsen, Birger Johnsen, Gert-Åke Hansson, Anders Fuglsang-Frederiksen, Poul Frost   +5 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Adverse effects of linezolid in the treatment of drug-resistant tuberculosis combined with diabetic peripheral neuropathy

European Journal of Medical Research
Objective This aimed to observe the adverse effects of linezolid on nerve conduction velocity in patients with drug-resistant tuberculosis combined with diabetic peripheral neuropathy.
Yanjun Li, Yanjing Feng, Zhiye Yin, Xianlei Wang, Yonghua Hou, Liwei Yu   +5 more
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Normative values and factors affecting saphenous nerve responses in a south Asian population: a cross-sectional neurophysiological study at a tertiary care hospital in Pakistan

BMC Neurology
Background The saphenous nerve, a sensory branch of the femoral nerve, is not commonly included in routine lower extremity nerve conduction studies due to a high frequency of non-recordable responses in healthy subjects.
Sajid Hameed, Bisma Aziz, Pinin Baig, Marib Ghulam Rasool Malik, Safia Awan, Sara Khan   +5 more
doaj   +1 more source

Bilateral nerve conduction studies must be considered in the diagnosis of sciatic nerve injury due to intramuscular injection

Neurological Sciences and Neurophysiology, 2020
Objectives: Although compound muscle action potential (CMAP) and sensory nerve action potential (SNAP) amplitudes of the nerves are reduced in sciatic nerve injury due to intramuscular injection (SNIII), they may still be higher than the reference values
Halit Fidanci, İlker Öztürk, Ahmet Candan Köylüoğlu, Mehmet Yıldız, Zülfikar Arlıer   +4 more
doaj   +1 more source

Node of Ranvier length as a potential regulator of myelinated axon conduction speed

eLife, 2017
Myelination speeds conduction of the nerve impulse, enhancing cognitive power. Changes of white matter structure contribute to learning, and are often assumed to reflect an altered number of myelin wraps. We now show that, in rat optic nerve and cerebral
I. Arancibia‐Carcamo, Marc C. Ford, L. Cossell, K. Ishida, K. Tohyama, D. Attwell   +5 more
semanticscholar   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Relationships of Nerve Conduction Parameters with the Thyroid Hormones in Hypothyroid Patients

Journal of Bangladesh Society of Physiologists, 2013
Background: Impairment of nerve conduction may occur in hypothyroidism which usually develops insidiously over a long period of time due to irregular taking of drugs or lack of thyroid hormone replacement.Objectives: To evaluate the thyroid hormone ...
Sabina Yeasmin, ,, Noorzahan Begum, Shelina Begum,, Shah Mohammed Hafizur Rahman   +3 more
doaj   +1 more source

How Nerves Conduct [PDF]

Nature, 1968
Nerve Excitation A Macromolecular Approach. By Ichiji Tasaki. Pp. xi + 201. (Thomas: Springfield, Ill., 1968.) $14.75.
openaire   +1 more source