Results 111 to 120 of about 529,256 (343)

Nerve conduction in relation to vibration exposure - a non-positive cohort study

open access: yesJournal of Occupational Medicine and Toxicology, 2010
Background Peripheral neuropathy is one of the principal clinical disorders in workers with hand-arm vibration syndrome. Electrophysiological studies aimed at defining the nature of the injury have provided conflicting results.
Nilsson Tohr   +6 more
doaj   +1 more source

What is the best diagnostic approach to paresthesias of the hand? [PDF]

open access: yes, 2002
There have been no good studies comparing different strategies for the evaluation of the patient with hand paresthesias. A reasonable strategy is to first evaluate for carpal tunnel syndrome (CTS), the most common condition associated with hand ...
Corrington, Kip A.   +2 more
core  

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

Prospective hospital-based clinical and electrophysiological evaluation of acute organophosphate poisoning

open access: yesAnnals of Indian Academy of Neurology, 2019
Introduction: Acute organophosphate (OP) poisoning is one of the most common poisoning causing significant morbidity and mortality in developing countries.
Karkal Ravishankar Naik   +3 more
doaj   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao   +10 more
wiley   +1 more source

Association of BMI, Waist-hip Ratio and Skinfold Thickness with Sensory Conduction of the Median Nerve in First-year Medical Students: A Cross-sectional Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Introduction: Nerve Conduction Study (NCS) is a widely used electrodiagnostic tool to evaluate the health of the peripheral nervous system. First-year medical students, due to extensive use of Information and Communications Technology (ICT) and academic ...
Seema V Kamaraddi   +2 more
doaj   +1 more source

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini   +7 more
wiley   +1 more source

The mechanosensitive ion channel TRAAK is localized to the mammalian node of Ranvier. [PDF]

open access: yes, 2019
TRAAK is a membrane tension-activated K+ channel that has been associated through behavioral studies to mechanical nociception. We used specific monoclonal antibodies in mice to show that TRAAK is localized exclusively to nodes of Ranvier, the action ...
Brohawn, Stephen   +5 more
core  

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas   +18 more
wiley   +1 more source

A mathematical model for calculating the effect of toroidal geometry on the measured magnetic field [PDF]

open access: yes, 2009
A mathematical model to calculate the measured magnetic field from a stimulated nerve has been presented in the past. Traditionally, electrodes have been used to measure these propagating action signals in nerves, but a less invasive technique is to use ...
Skoczelas, Brenda M.
core   +1 more source

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