Results 31 to 40 of about 83,231 (259)

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

The application of ultrasound guidance in electrodiagnostic studies – A narrative review

Journal of Medical Ultrasound, 2023
Electrodiagnostic studies, including nerve conduction study and electromyography, were conducted based on surface anatomy in a conventional manner. However, the anatomical variations and difficulty in the identification of target nerves or muscles render
Kuo-Chang Wei, Chueh-Hung Wu, Tyng-Guey Wang   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Electrophysiological Correlation of Motor Recovery Following Median and Ulnar Nerve Injuries: A Prospective Observational Study

Indian Journal of Physical Medicine & Rehabilitation
Background: A paucity of consensus still persists regarding the comparison of electrophysiological findings with clinical motor improvement pattern in hand function following traumatic nerve injuries in the distal forearm.
Siddhartha Sinha Ray, Ushnish Mukherjee, Aniketa Banerjee, Rajesh Pramanik   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Evaluation of Clinical Tests in Detecting Nerve Regeneration

مجله دانشکده پزشکی اصفهان, 2017
Background: There is not a perfect clinical nerve regeneration assessment test. Tinel’s test is an acknowledged test for clinical evaluation of nerve regeneration, but has significant imperfections.
Hamid Namazi, Meisam Bazgir
doaj  

Comparison Of Median Nerve Conduction Velocity Between Player Games (Gamers) And Non-Player Games Based On Electroneuromyography

Jurnal Profesi Medika, 2021
Playing games for a long period can induce a negative effect on the hands, especially on the median nerve. This study aims to compare median nerve conduction between gamers and non-gamers.
Ilsa Hunaifi, Herpan Syafii Harahap, Muhammad Galvan Sahidu, Triana Dyah Cahyawati   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Nerve conduction studies of median nerve in normal subjects

Journal of Health Science and Medical Research (JHSMR), 2005
Objective: To establish the normal electrophysiological values of the median nerve in normal healthy adult subjects. Material and Methods: Nerve conduction study was performed on the median nerve of 100 screened healthy adult volunteers using standard ...
W Permsirivanich, A Boonmeeprakob
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source