Results 61 to 70 of about 1,303,285 (347)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Clinical feature and sural biopsy study in nitrous oxide-induced peripheral neuropathy.

PLoS ONE, 2022
ObjectiveThe objective was to analyze the clinical characteristics and pathological characteristics of sural biopsy in nitrous oxide (N2O) -induced peripheral neuropathy.MethodsWe recruited 18 patients with N2O abuse-induced neurological disorders and ...
Qian Wang, Xiaohui Duan, Mingrui Dong, Shaojie Sun, Pan Zhang, Fang Liu, Li Wang, Renbin Wang   +7 more
doaj   +1 more source

Mean Motor Nerve Conduction Velocity of Right Ulnar Nerve among Physically Trained Adult Males in a Tertiary Care Centre: A Descriptive Cross-sectional Study

Journal of Nepal Medical Association, 2022
Introduction: Neural adaptation to physical training allows a person to better coordinate the activation of all relevant muscles producing maximum force.
Rekha Limbu, Nirmala Limbu, Rita Khadka, Priza Subedi, Dilmaya Limbu   +4 more
doaj   +1 more source

Design and Stability Analysis of an Electromechanical Model for Nerves [PDF]

arXiv, 2021
In this work, we propose and study the stability of nerve impulse propagation as electrical and mechanical signals through linear approximation. We present a potential energy stored in the biomembrane due to the deformation, bending, and stretching as the action potential propagates in the nerve fibre.
arxiv  

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

Nerve conduction studies of median nerve in normal subjects

Journal of Health Science and Medical Research (JHSMR), 2005
Objective: To establish the normal electrophysiological values of the median nerve in normal healthy adult subjects. Material and Methods: Nerve conduction study was performed on the median nerve of 100 screened healthy adult volunteers using standard ...
W Permsirivanich, A Boonmeeprakob
doaj  

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Evaluation of Clinical Tests in Detecting Nerve Regeneration

مجله دانشکده پزشکی اصفهان, 2017
Background: There is not a perfect clinical nerve regeneration assessment test. Tinel’s test is an acknowledged test for clinical evaluation of nerve regeneration, but has significant imperfections.
Hamid Namazi, Meisam Bazgir
doaj  

Reply to “Conduction studies on the sural nerve” [PDF]

Clinical Neurophysiology Practice, 2022
Krøigård, Thomas, Andersen, Kjeld V., Tankisi, Hatice, Beniczky, Sándor, Kristensen, Alexander Gramm   +4 more
openaire   +5 more sources

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

FEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei, Zhanbiao Liu, Jingjing Shi, Qian Jin, Wenqian Chen, Xuejun Chen, Liqin Li, Hui Chen   +7 more
wiley   +1 more source