Results 191 to 200 of about 2,615,361 (255)

Machine Learning‐Driven Design of Multicomponent Bone Inorganic Matrix Mimicking Scaffolds for Osteogenesis Enhanced by Neurogenesis

Advanced Science, EarlyView.
Schematic illustration of development of experimental datasets and algorithm models, screening and preparation of the scaffolds and their applications in vivo. ABSTRACT Bone defects require materials with osteogenic, neurogenic, and angiogenic activity, yet designing such materials within high‐dimensional compositional spaces remains challenging. Here,
Kunlu Lin, Ying Yang, Chuyao Zhou, Hanyue Mao, Zhiquan Zhang, Libangxi Liu, Xiaoying Yu, Haoming Liu, Long Liu, Xiaoyan Wang   +9 more
wiley   +1 more source

An Innervated Human Skin Equivalent that Electrically Encodes Mechanical and Thermal Stimuli

Advanced Science, EarlyView.
An innervated human skin equivalent is integrated with high‐density microelectrode arrays to reveal how engineered free nerve ending–like structures translate touch and temperature into electrical codes. Mechanical indentation and thermal stimulation engage the engineered somatosensory circuitry and evoke distinct firing and waveform signatures ...
Daniele Bellantoni, Costantino Casale, Marika Sperduti, Nevio L. Tagliamonte, Giorgia Imparato, Loredana Zollo, Paolo A. Netti   +6 more
wiley   +1 more source

Endothelial miR‐15a/16‐1 Regulation of SYNE1 Mediates Structural and Functional Recovery after Traumatic Brain Injury

Advanced Science, EarlyView.
Endothelial miR‐15a/16‐1 deletion promotes long‐term recovery after traumatic brain injury by restoring SYNE1 expression. Enhanced endothelial SYNE1 preserves vascular integrity, protects white and gray matter, and improves neurological function. The endothelial miR‐15a/16‐1–SYNE1 axis emerges as a key regulator of neurovascular repair and a potential ...
Shun Li, Na Qiu, Chao Zhou, Andrew Ni, Ping Sun, Jia‐Jun Liu, Xin‐Lei Huang, Tian‐Qing Xiong, Yu‐Chi Zhang, Hai‐Zhou Liu, Xiao‐Tao Xu, Rui Wang, Shi‐Qing Zhang, Yu‐Xin Zhang, Silvia Liu, C. Edward Dixon, Jun Chen, Ke‐Jie Yin   +17 more
wiley   +1 more source

Neuromorphic Devices and Computing for Sensing, Memory, and Control

Advanced Science, EarlyView.
This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu, Nicholas Schaffer, Xiao Yang   +2 more
wiley   +1 more source

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Evaluation of Nerve Fiber Layer Assessment

Archives of Ophthalmology, 1984
More than 1,400 eyes with either ocular hypertension glaucomatous visual field loss, or normal pressures and fields (controls) were studied prospectively in standardized, masked fashion. The appearance of the nerve fiber layer was evaluated independently from red-free photographs with the discs blocked-out by two observers.
A, Sommer, H A, Quigley, A L, Robin, N R, Miller, J, Katz, S, Arkell   +5 more
openaire   +2 more sources

The Nerve Fiber Layer in the Diagnosis of Glaucoma

Archives of Ophthalmology, 1977
Serial fundus photographs of 14 eyes that eventually developed glaucomatous visual field defects and 110 slides from 76 eyes of race- and age-matched controls were reviewed in randomized masked fashion. Each eye that lost visual field demonstrated consistent abnormalities of the nerve fiber layer, beginning as early as 5 years (mean, 1 1/2 years ...
A, Sommer, N R, Miller, I, Pollack, A E, Maumenee, T, George   +4 more
openaire   +2 more sources

Polarimetry of the retinal nerve fiber layer

Current Opinion in Ophthalmology, 1996
Retinal nerve fiber layer (RNFL) examination is a useful tool in the diagnosis and follow-up of glaucoma. Because the clinical techniques to date have been subjective, there is a definitive need to develop instruments that are capable of making accurate and reproducible measurements of the RNFL.
A, Tuulonen, P J, Airaksinen
openaire   +2 more sources

Evaluation of the retinal nerve fiber layer

Survey of Ophthalmology, 1996
In normal eyes, the retinal nerve fiber layer (RNFL) is usually best visible in the inferior temporal part of the fundus, followed by the superior temporal region, the nasal superior region and the nasal inferior region. This distribution correlates with the configuration of the neuroretinal rim, the diameter of the retinal arterioles, the location of ...
J B, Jonas, A, Dichtl
openaire   +2 more sources

Nerve fiber layer photography

Acta Ophthalmologica, 1987
Abstract. Observation of the retinal nerve fiber layer with red‐free light is an important means of evaluating optic nerve integrity. Many investigators have attempted to increase the usefulness of the technique by improving photographic procedures.
E, Peli, T R, Hedges, T, McInnes, J, Hamlin, B, Schwartz   +4 more
openaire   +2 more sources

Optic Nerve Head and Nerve Fiber Layer in Alzheimer's Disease

Archives of Ophthalmology, 1991
We compared (1) the differences in the retinal nerve fiber layer between 26 patients with Alzheimer's disease and 30 age- and race-matched normal controls with use of blue-light high-resolution photography, (2) the differences in disc pallor between 30 patients with Alzheimer's disease and 32 controls with use of a boundary-tracking program and fundus ...
C S, Tsai, R, Ritch, B, Schwartz, S S, Lee, N R, Miller, T, Chi, F Y, Hsieh   +6 more
openaire   +2 more sources