JOR SpineBackground Disc degeneration is associated with repetitive violent injuries. This study aims to explore the impact of repetitive strikes loading on the biology and biomechanics of intervertebral discs (IVDs) using an organ culture model.
Jiaxiang Zhou +12 more
doaj +1 more source
Long-term functional recovery after facial nerve transection and repair in the rat [PDF]
, 2015 BACKGROUND: The rodent model is commonly used to study facial nerve injury. Because of the exceptional regenerative capacity of the rodent facial nerve, it is essential to consider the timing when studying facial nerve regeneration and functional ...
Banks, Caroline A +5 more
core +2 more sources
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Facial Nerve Axotomy in Mice: A Model to Study Motoneuron Response to Injury [PDF]
, 2015 The goal of this surgical protocol is to expose the facial nerve, which innervates the facial musculature, at its exit from the stylomastoid foramen and either cut or crush it to induce peripheral nerve injury.
Batka, Richard J. +5 more
core +1 more source
G9a participates in nerve injury-induced Kcna2 downregulation in primary sensory neurons
Scientific Reports, 2016 Nerve injury-induced downregulation of voltage-gated potassium channel subunit Kcna2 in the dorsal root ganglion (DRG) is critical for DRG neuronal excitability and neuropathic pain genesis.
Lingli Liang +10 more
semanticscholar +1 more source
Oral Administration of the p75 Neurotrophin Receptor Modulator, LM11A-31, Improves Erectile Function in a Mouse Model of Cavernous Nerve Injury [PDF]
, 2020 Guo Nan Yin +8 more
openalex +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Neuromyelitis Optica Spectrum Disorder (NMOSD) is a chronic autoimmune neuroinflammatory disease, typically characterized by antibodies against aquaporin 4 (AQP4‐IgG) or myelin oligodendrocyte glycoprotein (MOG‐IgG). Simultaneous seropositivity for both antibodies in a single patient is exceedingly rare.
Yeting Luo, Shuhua Xie, Xianghong Liu
wiley +1 more source
An examination of walking track analysis footprints of right-side unoperated limbs in rats prior to and following peripheral nerve injury and PEG fusion repair [PDF]
, 2018 Peripheral nerve injury can result in long-lasting functional deficits in humans due to mammals’ limited axon regenerative capacity. PEG fusion is a defined technique that fuses injured axons, resulting in morphological and electrophysiological ...
Jagannath, Karthik
core +1 more source
Scientific Reports, 2016 Peripheral nerve injury is a global problem that causes disability and severe socioeconomic burden. Brain-derived neurotrophic factor (BDNF) benefits peripheral nerve regeneration and becomes a promising therapeutic molecule.
Sheng Yi +7 more
semanticscholar +1 more source
Improvement of lung ischemia–reperfusion injury by inhibition of microRNA‐155 via reductions in neuroinflammation and oxidative stress of vagal afferent nerve [PDF]
, 2020 Yan Zhou +3 more
openalex +1 more source