Results 121 to 130 of about 4,697,577 (350)
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
Physical Activity Modulates Corticospinal Excitability of the Lower Limb in Young and Old Adults [PDF]
, 2017 Aging is associated with reduced neuromuscular function, which may be due in part to altered corticospinal excitability. Regular physical activity (PA) may ameliorate these age-related declines, but the influence of PA on corticospinal excitability is ...
Hassanlouei, Hamidollah +4 more
core +1 more source
Nerve Excitability Test (NET) in Patients with Facial Palsy.
Practica Oto-Rhino-Laryngologica, 1994 Five patients with Ramsay Hunt's syndrome and 14 with Bell's palsy were evaluated with facial scores (full score: 40) and the nerve excitability test (NET) to determine the method of therapy, including decompression surgery. ATP, vitamin B1, 6, 12 and hydrocortisone were administrated and vidarabine was added in the treatment of patients with Ramsay ...
Taku HATTORI, Kiyotaka ASAMI, Keiko HIBI
openaire +2 more sources
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
PRIMITIVE NERVOUS SYSTEMS. A SENSORY NERVE-NET IN THE POLYCLAD FLATWORM NOTOPLANA ACTICOLA
, 1973 (1). The response to mechanical stimuli in the polyclad flatworm, Notoplana acticola, is the initiation of ditaxic locomotion. The response to electrical stimuli is local contraction.(2).
H. Koopowitz
semanticscholar +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini +7 more
wiley +1 more source
PLoS ONE, 2012 The treatment of critical size peripheral nerve defects represents one of the most serious problems in neurosurgery. If the gap size exceeds a certain limit, healing can't be achieved. Connection mismatching may further reduce the clinical success.
Stefan Weigel +7 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini +13 more
wiley +1 more source