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Peripheral Nerve Regeneration

Neurosurgery Clinics of North America, 1991
The success of peripheral nerve regeneration is dependent on the survival of axotomized neurons, the efficacy of axonal outgrowth from those neurons, and the specificity of reinnervation of peripheral targets by those neurons. Experimental evidence indicates that following peripheral injury, primary sensory (DRG) neurons and in some cases, motoneurons ...
F J, Liuzzi, B, Tedeschi
openaire   +2 more sources

Nerve regeneration

Current Opinion in Neurology, 1995
The regeneration of nerve is a brilliant example of plasticity within the nervous system. Axonal sprouts form within a few hours of nerve injury and grow vigorously over long distances. Nonetheless, recovery from nerve injury, such as that seen after laceration of distal motor-sensory nerve, is often incomplete.
openaire   +2 more sources

Electrical stimulation to enhance peripheral nerve regeneration: Update in molecular investigations and clinical translation.

Experimental Neurology, 2020
Peripheral nerve injuries are common and frequently result in incomplete functional recovery even with optimal surgical treatment. Permanent motor and sensory deficits are associated with significant patient morbidity and socioeconomic burden.
Kevin J. Zuo   +3 more
semanticscholar   +1 more source

Peripheral nerve regeneration

Neuroscience Research, 1996
Peripheral nerve regeneration comprises the formation of axonal sprouts, their outgrowth as regenerating axons and the reinnervation of original targets. This review focuses on the morphological features of axonal sprouts at the node of Ranvier and their subsequent outgrowth guided by Schwann cells or by Schwann cell basal laminae.
openaire   +2 more sources

Electrospinning Multilayered Scaffolds Loaded with Melatonin and Fe3O4 Magnetic Nanoparticles for Peripheral Nerve Regeneration

Advanced Functional Materials, 2020
Peripheral nerve injury is a common clinical problem bringing heavy burden to patients, due to its high incidence and unsatisfactory treatment. Nerve guidance conduit (NGC) is a promising scaffold for peripheral nerve repair, and bioactive agents are ...
Xuan Chen   +7 more
semanticscholar   +1 more source

Peripheral Nerve Regeneration

JAMA: The Journal of the American Medical Association, 1972
To the Editor— Rix's letter (217:480, 1971) recommending primary nerve repair in combined nerve and tendon lacerations, and the subsequent letters of Raskind et al (217:1864, 1971) and Cramer (219:1213, 1972) presented interesting discussions of the management of peripheral nerve injuries.
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Challenges to nerve regeneration

Seminars in Surgical Oncology, 2000
Peripheral nerve injuries can result from mechanical, thermal, chemical, congenital, or pathological etiologies. Failure to restore these damaged nerves can lead to the loss of muscle function, impaired sensation, and painful neuropathies. Current surgical strategies for the repair of critical nerves involve the transfer of normal donor nerve from an ...
openaire   +2 more sources

Regeneration in the VIII Nerve

Acta Oto-Laryngologica, 1976
After transection of the VIII nerve in the inner meatus, 95% of the cochlear neurons and practically all efferent fibres degenerate and disappear. In long-term survivals, different phenomena indicate the regeneration properties of many, probably efferent or vestibular nerve fibres. The few remaining afferent neurons react to the lesion of their central
H, Spoendlin, R, Suter
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Functional Polymer‐Based Nerve Guide Conduits to Promote Peripheral Nerve Regeneration

Advanced Materials Interfaces, 2020
Bridging critical‐sized defects in peripheral nerves to achieve functional recovery is a challenge for orthopedic and hand surgeons. Inadequate regeneration of peripheral nerve axons often results in long‐term partial or total sensory and/or motor ...
Xi Zhang   +8 more
semanticscholar   +1 more source

3D structured self-powered PVDF/PCL scaffolds for peripheral nerve regeneration

, 2020
Piezoelectric materials providing in situ electrical stimulation (ES) without applying an external chemical or physical supporting open new frontiers for future bioelectric therapies.
Yuan Cheng   +5 more
semanticscholar   +1 more source

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