Results 141 to 150 of about 1,893,805 (368)

Neurodevelopmental Stimulation of a Child with a Noonan Syndrome with a Non-Frequent Mutation in RAF1 Gene — Case Report

open access: yesPielęgniarstwo Neurologiczne i Neurochirurgiczne, 2019
Introduction. Noonan syndrome (NS) is a genetically determined disease, inherited from autosomal dominant. About 50% of patients have a mutation in the PTPN11 gene, and mutations in the other genes are much less frequent, up to 10–15% for SOS1, RAF1, and
Teresa Kaczan   +4 more
doaj   +1 more source

A Mathematical Model for Skin Sympathetic Nerve Activity Simulation [PDF]

open access: yesarXiv
Autonomic nervous system is important for cardiac function regulation. Modeling of autonomic cardiac regulation can contribute to health tracking and disease management. This study proposed a mathematical model that simulates autonomic cardiac regulation response to Valsalva Maneuver, which is a commonly used test that provokes the autonomic nervous ...
arxiv  

A PANoptosis‐Based Signature for Survival and Immune Predication in Glioblastoma Multiforme

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PANoptosis is a concept of total cell death characterized by pyroptosis, apoptosis, and necroptosis. We aimed to explore the clinical significance of PANoptosis‐related genes (PARGs) in glioblastoma multiforme (GBM). Methods Expression profiles of GBM were downloaded from the XENA database as a training dataset to construct a ...
Jun Yang   +4 more
wiley   +1 more source

A Sympathetic Nervous System Theory of Migraine [PDF]

open access: yesarXiv
Migraine (MGR) ranks first among diseases in terms of years of lost healthy life in young adult and adult women. Currently, there is no theory of MGR. This paper presents a complete theory of migraine that explains its etiology, symptoms, pathology, and treatment.
arxiv  

Pharmacokinetics, Efficacy, and Safety of Upadacitinib in Pediatric Patients With Polyarticular‐Course Juvenile Idiopathic Arthritis: An Interim Analysis of an Open‐Label, Phase 1 Trial

open access: yesArthritis Care &Research, Volume 77, Issue 5, Page 584-593, May 2025.
Objective This work aimed to evaluate the pharmacokinetics, efficacy, and safety of upadacitinib, an oral selective JAK inhibitor, in pediatric patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods In an open‐label, phase 1 study (SELECT‐YOUTH), enrolled patients, aged 2 to <18 years with pcJIA, received body weight–based ...
Hermine I. Brunner   +12 more
wiley   +1 more source

DISEASES OF THE NERVOUS SYSTEM

open access: yesThe Journal OF Nervous and Mental Disease, 1908
Mode of access: Internet.
openaire   +3 more sources

Exosomal MicroRNA Signatures in Central Nervous System Diseases [PDF]

open access: yes, 2018
During the last decade there has been a growing interest in studying extracellular vesicles, in particular exosomes and their miRNA contents. Exosomes are released by almost all cell types.
Ebrahimkhani, Saeideh
core  

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