Neuroprotective Effects of Anthraquinones from Rhubarb in Central Nervous System Diseases
Evidence-Based Complementary and Alternative Medicine, 2019 Rhubarb is a well-known traditional Chinese medicine; it has been used in China for thousands of years. Rhubarb anthraquinones are the major medicinal ingredients derived from rhubarb including emodin, aloe-emodin, chrysophanol, rhein, physcion, and ...
Xun Li +3 more
semanticscholar +1 more source
Identification of Dementia With Lewy Bodies by Skin Biopsy in Recent‐Onset Cognitive Impairment
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Immunofluorescence for phosphorylated alpha‐synuclein in skin biopsy samples is an emerging biomarker in synucleinopathies comprising Dementia with Lewy bodies. In this pilot study, 19 patients with recent‐onset (≤ 18 months) cognitive impairment underwent skin biopsy at baseline, with follow‐up clinical re‐evaluation.
Alessandro Furia +13 more
wiley +1 more source
Discovery and Treatment of Action Potential‐Independent Myotonia in Hyperkalemic Periodic Paralysis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hyperkalemic periodic paralysis (hyperKPP) is characterized by attacks of transient weakness. A subset of hyperKPP patients suffers from transient involuntary contraction of muscle (myotonia). The goal of this study was to determine mechanisms causing myotonia in hyperKPP.
Chris Dupont +4 more
wiley +1 more source
Backgrounds of Speech Disorders in Children with Down Syndrome. An Early Logopedic Intervention
Pielęgniarstwo Neurologiczne i Neurochirurgiczne, 2016 Speech development of children with a Down syndrome is partly stunted or disturbed in comparison to healthy children’s speech, although, it is subjected to the same rules.
Teresa Kaczan +2 more
doaj +1 more source
An Address on Trauma in Relation to Disease of the Nervous System: Presidential Address to the Manchester Medical Society [PDF]
, 1904 J. S. Bury
openalex +1 more source
The Gut-Microglia Connection: Implications for Central Nervous System Diseases
Frontiers in Immunology, 2018 The importance of the gut microbiome in central nervous system (CNS) diseases has long been recognized; however, research into this connection is limited, in part, owing to a lack of convincing mechanisms because the brain is a distant target of the gut.
Yiliang Wang +10 more
semanticscholar +1 more source
Digital Activity Markers in Chronic Inflammatory Demyelinating Polyneuropathy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the utility of smartwatch and smartphone‐based activity metrics for assessing disease severity and quality of life in patients with chronic inflammatory demyelinating polyneuropathy (CIDP). Methods In the electronic monitoring of disease activity in patients with CIDP (EMDA‐CIDP) trial, we performed a prospective ...
Lars Masanneck +15 more
wiley +1 more source
Signal Transduction Pathways of Acupuncture for Treating Some Nervous System Diseases
Evidence-Based Complementary and Alternative Medicine, 2019 In this article, we review signal transduction pathways through which acupuncture treats nervous system diseases. We electronically searched the databases, including PubMed, MEDLINE, clinical Key, the Cochrane Library, and the China National Knowledge ...
H. Lai, Q. Chang, C. Hsieh
semanticscholar +1 more source
Multimodal Autonomic Biomarkers Predict Phenoconversion in Pure Autonomic Failure
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Pure autonomic failure (PAF) presents with autonomic failure without other neurological features. A third develop central neurological features, fulfilling criteria for multiple system atrophy (MSA) and Lewy body diseases (LBD), including Parkinson's disease and Dementia with Lewy bodies.
S. Koay +12 more
wiley +1 more source
Root Mean Square Error of Neural Spike Train Sequence Matching with Optogenetics
, 2017 Optogenetics is an emerging field of neuroscience where neurons are genetically modified to express light-sensitive receptors that enable external control over when the neurons fire.
Eckford, Andrew W. +2 more
core +1 more source