Results 261 to 270 of about 124,681 (307)

Animal models of central nervous system disorders

Handbook of Innovations in Central Nervous System Regenerative Medicine, 2020
Animal models have been extensively used to study the complex physiology and pathophysiology of human diseases. They are valuable for understanding biological phenomena, to understand disease development and progression, and for testing novel therapeutic
Eduardo D. Gomes, Sandra Barata-Antunes, A. Teixeira-Castro, R. Assunção-Silva, C. R. Marques, S. Monteiro, F. Teixeira, A. Fernandes, N. Silva   +8 more
semanticscholar   +1 more source

Current modeling approaches for drug delivery to the central nervous system.

Therapeutic delivery
Central nervous system (CNS) disorders pose a major global health challenge, yet therapeutic development is impeded by the difficulty of delivering effective drug concentrations to the brain.
Shoaib A. Goraya, Abraham R Tzafriri, C. Guttmann, Farhad R. Nezami   +3 more
semanticscholar   +1 more source

ASSESSMENT OF PHYSIOLOGICAL PARAMETERS OF THE TRIGEMINAL AND COCHLEOVESTIBULAR SYSTEMS IN TEMPOROMANDIBULAR JOINT PAIN DYSFUNCTION

Journal of Ural Medical Academic Science, 2020
One of the most common causes of chronic pain in the facial region, including in the trigeminal nerve link, which is not associated with dental diseases, is pain dysfunction of the temporomandibular joint.
N. D. Sorokina, Dentistry named after E.I. Evdokimov, L. R. Shahalieva, S. Pertsov, L. Polma, G. V. Selitsky   +5 more
semanticscholar   +1 more source

The Trail of axonal protein Synthesis: Origins and current functional Landscapes.

Neuroscience
Local protein synthesis (LPS) in axons is now recognized as a physiological process, participating both in the maintenance of axonal function and diverse plastic phenomena. In the last decades of the 20th century, the existence and function of axonal LPS
J. Garat, A. Paolo, Guillermo Eastman, Pablo E. Castillo, J. Sotelo-Silveira   +4 more
semanticscholar   +1 more source

Multidimensional dynamic optical imaging unveils anesthetic-driven hemispheric lateralization in blood-brain barrier homeostasis

Science Advances
The blood-brain barrier (BBB) is commonly known to be distributed evenly within the central nervous system. This study elucidates previously unexplored physiological phenomena associated with the spatial heterogeneity of the BBB. We found that isoflurane
Honghui Li, Mingyang Sun, Bowen Zhu, Jiali Chen, Weiran Pang, Ziyuan Tang, Qi Zhou, Zhiyao Han, Laiyou Wang, Fengxian Li, Jiaqiang Zhang, Liming Nie   +11 more
semanticscholar   +1 more source

Biological agency: a concept without a research program.

Journal of Evolutionary Biology
This paper evaluates recent work purporting to show that the "agency" of organisms is an important phenomenon for evolutionary biology to study. Biological agency is understood as the capacity for goal-directed, self-determining activity-a capacity that ...
J. DiFrisco, Richard Gawne
semanticscholar   +1 more source

Physiological relevance and functional potential of central nervous system-derived cell lines

Molecular Neurobiology, 1996
S. Whittemore, E. Snyder
semanticscholar   +1 more source

Role of leukemia inhibitory factor in the nervous system and its pathology

Reviews in the Neurosciences, 2015
P. Ostašov, Zbyněk Houdek, J. Cendelin, M. Králíčková   +3 more
semanticscholar   +1 more source

Physiological Detection of Satisfaction for Services by Body Motion Wave Revealing Unconscious Responses Reflecting Activities of Autonomic Nervous Systems

International Conference on Serviceology, 2015
H. Okawai, M. Takashima
semanticscholar   +1 more source