Results 161 to 170 of about 1,752 (196)
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Nesidioblastosis (diagnosis, surgical treatment)
Khirurgiya. Zhurnal im. N.I. Pirogova, 2015Nesidioblastosis (NB) is rare disease with organic hyperinsulinism syndrome and caused by diffuse hyperplasia and/or hypertrophy of pancreatic islands of Langerhans.The results of surgical treatment of 3 patients with NB are presented. In all patients the diagnosis was suspected at the preoperative stage and confirmed by histological examination later.
A G, Kriger +8 more
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Nesidioblastosis: A Case Study
The Journal of Perinatal & Neonatal Nursing, 1998Hypoglycemia is a frequent problem in the neonatal period requiring close attention and intervention. Severe, persistent hypoglycemia can have various etiologies; one of the most common causes is hyperinsulinism. Nesidioblastosis, although rare, is the most common cause of hyperinsulinism in the neonate. If not detected early, nesidioblastosis can lead
C H, Kistler, K, Spiering
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Alloxan therapy for nesidioblastosis
Journal of Pediatric Surgery, 1984Two patients with nesidioblastosis presented to the Royal Hospital for Sick Children in Glasgow and developed recurrent hypoglycemia after subtotal pancreatectomy. They were treated successfully with alloxan (mesoxalyl urea). Alloxan is recommended as an alternative to further radical surgery.
P M, Davidson +4 more
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Pancreatic Nesidioblastosis in Adults
Diabetes Care, 1989Nesidioblastosis, a condition characterized by diffuse islet cell hyperplasia arising from the ductal epithelium, is often associated with hyperinsulinemic hypoglycemia. This is a childhood disease and is rarely found in adults. Only 10 histologically proven cases have been recorded, including 3 new cases described in this article.
T L, Fong, N E, Warner, D, Kumar
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Archives of Surgery, 1981
Nesidioblastosis is the leading cause of hyperinsulinemia in newborns and infants. To our knowledge, it has not been previously reported in adults unless associated with other diseases. Three males and three females, aged 11 to 57 years, are described. Pancreatic resections ranged from 50% to 100%.
J K, Harness +7 more
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Nesidioblastosis is the leading cause of hyperinsulinemia in newborns and infants. To our knowledge, it has not been previously reported in adults unless associated with other diseases. Three males and three females, aged 11 to 57 years, are described. Pancreatic resections ranged from 50% to 100%.
J K, Harness +7 more
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Nesidioblastosis in a Simmental Calf
Journal of Comparative Pathology, 2012A 2-day-old Simmental calf with arthrogryposis and astasia was subjected to necropsy examination. The calf was normoglycaemic and normoinsulinaemic. Microscopically, pancreatic tissue was hyperplastic with an irregular lobular arrangement of pancreatic islets.
Gacar, A. +4 more
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Nesidioblastosis in Sickle Cell Disease
Fetal and Pediatric Pathology, 2001Although the endocrine pancreas appears to play an important role in the pathophysiology of sickle cell disease, very little is known about the morphologic changes in this tissue. Our study was initiated to delineate the microscopic features of the endocrine pancreas in a large autopsy series of sickle cell hemoglobinopathies.
D E, Culberson +6 more
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Nesidioblastosis in an Elderly Patient
Diabetic Medicine, 1995We report an 84‐year‐old woman with hypoglycaemia and hyperinsulinaemia caused by diffuse nesidioblastosis. This is the oldest case of nesidioblastosis so far recorded. The case illustrates some of the difficulties in diagnosing inappropriate hyperinsulinaemia and the benefits of surgery, even in old age.
D, Walmsley +4 more
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Familial nesidioblastosis in two sisters
Surgery Today, 1995We herein present two female siblings with persistent hyperinsulinemic hypoglycemia in the neonatal period who were diagnosed as having familial nesidioblastosis. Despite both the administration of diazoxide and the intravenous infusion of glucose, one of the affected infants died of severe metabolic acidosis at about 1 month of age, before ...
M, Yagi +4 more
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Adult Pancreatic Nesidioblastosis
Archives of Surgery, 1994Adult nesidioblastosis remains an uncommon and poorly understood condition creating both diagnostic and therapeutic dilemmas for clinicians. Despite the totipotent nature of hyperplastic pancreatic cells, nearly all accounts of nesidioblastosis described patients with symptoms of hypoglycemia.
D R, Farley +2 more
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