Results 161 to 170 of about 1,805 (193)

Pancreatic Nesidioblastosis in Adults

Diabetes Care, 1989
Nesidioblastosis, a condition characterized by diffuse islet cell hyperplasia arising from the ductal epithelium, is often associated with hyperinsulinemic hypoglycemia. This is a childhood disease and is rarely found in adults. Only 10 histologically proven cases have been recorded, including 3 new cases described in this article.
T L, Fong, N E, Warner, D, Kumar
openaire   +2 more sources

Nesidioblastosis in Adults

Archives of Surgery, 1981
Nesidioblastosis is the leading cause of hyperinsulinemia in newborns and infants. To our knowledge, it has not been previously reported in adults unless associated with other diseases. Three males and three females, aged 11 to 57 years, are described. Pancreatic resections ranged from 50% to 100%.
J K, Harness, G W, Geelhoed, N W, Thompson, R H, Nishiyama, S S, Fajans, R O, Kraft, D R, Howard, K A, Clark   +7 more
openaire   +2 more sources

Nesidioblastosis in a Simmental Calf

Journal of Comparative Pathology, 2012
A 2-day-old Simmental calf with arthrogryposis and astasia was subjected to necropsy examination. The calf was normoglycaemic and normoinsulinaemic. Microscopically, pancreatic tissue was hyperplastic with an irregular lobular arrangement of pancreatic islets.
Gacar, A., Pekmezci, D., Karayigit, M. O., Kabak, Y. B., Gulbahar, M. Y.   +4 more
openaire   +3 more sources

Nesidioblastosis in Sickle Cell Disease

Fetal and Pediatric Pathology, 2001
Although the endocrine pancreas appears to play an important role in the pathophysiology of sickle cell disease, very little is known about the morphologic changes in this tissue. Our study was initiated to delineate the microscopic features of the endocrine pancreas in a large autopsy series of sickle cell hemoglobinopathies.
D E, Culberson, E A, Manci, A K, Shah, J, Haynes, S K, Ballas, C, Pegelow, E, Vichinsky   +6 more
openaire   +2 more sources

Nesidioblastosis in an Elderly Patient

Diabetic Medicine, 1995
We report an 84‐year‐old woman with hypoglycaemia and hyperinsulinaemia caused by diffuse nesidioblastosis. This is the oldest case of nesidioblastosis so far recorded. The case illustrates some of the difficulties in diagnosing inappropriate hyperinsulinaemia and the benefits of surgery, even in old age.
D, Walmsley, N A, Matheson, S, Ewen, R L, Himsworth, J S, Bevan   +4 more
openaire   +2 more sources

Familial nesidioblastosis in two sisters

Surgery Today, 1995
We herein present two female siblings with persistent hyperinsulinemic hypoglycemia in the neonatal period who were diagnosed as having familial nesidioblastosis. Despite both the administration of diazoxide and the intravenous infusion of glucose, one of the affected infants died of severe metabolic acidosis at about 1 month of age, before ...
M, Yagi, K, Shiraiwa, M, Abiko, H, Sakuma, S, Hirai   +4 more
openaire   +2 more sources

Adult Pancreatic Nesidioblastosis

Archives of Surgery, 1994
Adult nesidioblastosis remains an uncommon and poorly understood condition creating both diagnostic and therapeutic dilemmas for clinicians. Despite the totipotent nature of hyperplastic pancreatic cells, nearly all accounts of nesidioblastosis described patients with symptoms of hypoglycemia.
D R, Farley, J A, van Heerden, J L, Myers   +2 more
openaire   +2 more sources

Surgical treatment of nesidioblastosis

Pediatric Surgery International, 1986
This report comprises ten children with hyperinsulinaemic hypoglycaemia who did not respond to medical management and required surgical treatment. Eight were infants under the age of 1 year while two were children aged 3.5 and 5 years, respectively.
L. Spitz, R.G. Buick, D.B. Grant, J.V. Leonard, J.R. Pincott   +4 more
openaire   +1 more source

Nesidioblastosis with necrotising enterocolitis: an enigma

Pediatric Surgery International, 2000
Necrotising enterocolitis with nesidioblastosis is a rare, lethal coexistence during the newborn period. We report this unusual combination leading to surgery: a partial pancreatectomy and resection with primary anastomosis, and discuss the dilemma of the procedure of choice during therapy.
M S, Kulkarni, V A, Upadhyay
openaire   +2 more sources

[Experiences with nesidioblastosis].

Zentralblatt fur Chirurgie, 1991
Highly differentiated processes relating to insulin-generating cells of the endocrine pancreas are covered by the term of nesidioblastosis. The disease is primarily characterised by persistent hypoglycaemia, and it affects newborns and young infants. Diffuse nesidioblastosis is predominant, as compared to focal processes.
E, Gottschalk, H, Lüders, G, Scheerschmidt, A, Hauch   +3 more
openaire   +1 more source