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Anaesthetic management of a neonate with nesidioblastosis

Paediatric Anaesthesia, 1996
SummaryNesidioblastosis is a disorder which is characterized by autonomous insulin secretion that is not affected by decreases in blood glucose. Patients usually present during the neonatal or infantile period with hypoglycaemia associated with hyperinsulinaemia.
Stephen Stayer
exaly   +3 more sources

Nesidioblastosis in Children

Archives of Surgery, 1980
Three cases in which seizure disorder was first noticed were examined in the last seven years; low fasting glucose and high serum insulin levels then led to the diagnosis of severe hypoglycemia secondary to nesidioblastosis. Hypoglycemic episodes were uncontrolled by frequent oral feedings and intravenous administration of dextrose, glucagon, and ...
J, Knight   +4 more
openaire   +2 more sources

Nesidioblastosis: A Case Study

The Journal of Perinatal & Neonatal Nursing, 1998
Hypoglycemia is a frequent problem in the neonatal period requiring close attention and intervention. Severe, persistent hypoglycemia can have various etiologies; one of the most common causes is hyperinsulinism. Nesidioblastosis, although rare, is the most common cause of hyperinsulinism in the neonate. If not detected early, nesidioblastosis can lead
C H, Kistler, K, Spiering
openaire   +2 more sources

Nesidioblastosis in a Simmental Calf

Journal of Comparative Pathology, 2012
A 2-day-old Simmental calf with arthrogryposis and astasia was subjected to necropsy examination. The calf was normoglycaemic and normoinsulinaemic. Microscopically, pancreatic tissue was hyperplastic with an irregular lobular arrangement of pancreatic islets.
Gacar, A.   +4 more
openaire   +3 more sources

Nesidioblastosis in Adults

Archives of Surgery, 1981
Nesidioblastosis is the leading cause of hyperinsulinemia in newborns and infants. To our knowledge, it has not been previously reported in adults unless associated with other diseases. Three males and three females, aged 11 to 57 years, are described. Pancreatic resections ranged from 50% to 100%.
J K, Harness   +7 more
openaire   +2 more sources

Beta cell nesidioblastosis

European Journal of Pediatrics, 1978
Two patients with severe hypoglycemia since birth are described. In both hyperinsulinism was demonstrated during spontaneous hypoglycemic attacks or could be provoked by various tolerance tests. In case I considerable obesity and psychomotor retardation was present at the age of one year whereas in case II weight gain was normal and development ...
K, Becker   +5 more
openaire   +2 more sources

Hypoglycemia of Infancy and Nesidioblastosis

New England Journal of Medicine, 1977
We treated a two-month-old infant with servere intractable hypoglycemia and nesidioblastosis with continuous glucose infusions (0.75 g per kilogram per hour) via a central venous catheter. Preprandial glucose levels on this regimen were 37+/-2 mg per deciliter (+/-S.E.M.).
H J, Hirsch   +5 more
openaire   +2 more sources

Familial nesidioblastosis in two sisters

Surgery Today, 1995
We herein present two female siblings with persistent hyperinsulinemic hypoglycemia in the neonatal period who were diagnosed as having familial nesidioblastosis. Despite both the administration of diazoxide and the intravenous infusion of glucose, one of the affected infants died of severe metabolic acidosis at about 1 month of age, before ...
M, Yagi   +4 more
openaire   +2 more sources

Nesidioblastosis (diagnosis, surgical treatment)

Khirurgiya. Zhurnal im. N.I. Pirogova, 2015
Nesidioblastosis (NB) is rare disease with organic hyperinsulinism syndrome and caused by diffuse hyperplasia and/or hypertrophy of pancreatic islands of Langerhans.The results of surgical treatment of 3 patients with NB are presented. In all patients the diagnosis was suspected at the preoperative stage and confirmed by histological examination later.
A G, Kriger   +8 more
openaire   +2 more sources

Nesidioblastosis and the Zollinger-Ellison syndrome

The American Journal of Digestive Diseases, 1968
The most common cause of the Zollinger-Ellison syndrome is the over-production of a gastrin-like hormone by a non-beta islet cell neoplasm of the pancreas. Hyperplasia and neoformation of islets alone and in combination with neoplasia have been reported in association with the syndrome, but there has been little effort to implicate these findings in ...
R E, Brown, W J, Still
openaire   +2 more sources

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