Glucagon receptor gene mutations with hyperglucagonemia but without the glucagonoma syndrome
Pancreatic neoplasms producing exclusively glucagon associated with glucagon cell hyperplasia of the islets and not related to hereditary endocrine syndromes have been recently described.
Cohen, P +8 more
core +1 more source
Histological insights into the pathogenesis of post‐Roux‐en‐Y hyperinsulinaemic hypoglycaemia [PDF]
Background β‐cell hyperplasia has been implicated in the aetiology of post Roux‐en‐Y gastric bypass hyperinsulinaemic hypoglycaemia, but the pathogenesis of this condition is still unclear. Case report We report a case of a 52‐year‐old man with post‐
Giordano, T. J. +3 more
core +1 more source
Nesidioblastosis and Insulinoma: A Rare Coexistence and a Therapeutic Challenge
Background: Nesidioblastosis and insulinoma are disorders of the endocrine pancreas causing endogenous hyperinsulinemic hypoglycemia. Their coexistence is very unusual and treatment represents a still unresolved dilemma.Case Description: The patient was ...
Angela Dardano +7 more
doaj +1 more source
Laparoscopic Adjustable Gastric Banding and Hypoglycemia [PDF]
Obesity is commonplace, and surgical treatment usually includes Roux-en-Y gastric bypasses (RYGBs). RYGBs have the most documented side effects including vitamin deficiencies, rebound weight gain, and symptomatic hypoglycemia; fewer series exist ...
Bairdain, Sigrid +5 more
core +1 more source
A Large Animal Survival Model to Evaluate Bariatric Surgery Mechanisms [PDF]
BACKGROUND: The impact of Roux-en-Y gastric bypass (RYGB) on type 2 diabetes mellitus is thought to result from upper and/or lower gut hormone alterations.
Alloosh, Mouhamad +7 more
core +2 more sources
Glucagon-like peptide-1 (GLP-1) receptors are not overexpressed in pancreatic islets from patients with severe hyperinsulinaemic hypoglycaemia following gastric bypass [PDF]
Aims/hypothesis: Glucagon-like peptide-1 (GLP-1) receptors are highly overexpressed in benign insulinomas, permitting in vivo tumour visualisation with GLP-1 receptor scanning.
Callery, M. +7 more
core
Patologia molecular do receptor de sulfoniluréia (SUR1) [PDF]
The sulfonylurea receptor is a subunit of the ATP-sensitive potassium channel, which is expressed in the pancreatic beta cell. The central role of this receptor in glucose-induced insulin secretion was confirmed by description that mutations in this gene
Reis, André Fernandes [UNIFESP] +1 more
core +2 more sources
A propósito de un caso : paciente con cuadro de disartria de una hora y media de evolución [PDF]
Insulinoma is a neoplasia of pancreatic β-cells that secretes insulin. It constitutes a rare cause of hypoglycemia. Poor knowledge of this disease is explained by the low incidence, 4 in 1 million people per year. The nonspecific symptoms and its size
Roldán Vásquez, Ana María
core
Bariatric surgery and diabetes remission: Sleeve gastrectomy or mini-gastric bypass? [PDF]
AIM: To investigate the weight loss and glycemic control status [blood glucose, hemoglobin A1c (HbA1c) and hypoglycaemic treatment]. METHODS: The primary risk factor for type 2 diabetes is obesity, and 90% of all patients with type 2 diabetes are ...
Bianco P +10 more
core +1 more source
Persistent hyperinsulinemic hypoglycemia of infancy: An overview of current concepts
Persistent hyperinsulinemic hypoglycemia of infancy (PHHI) is relatively rare but one of the most important causes of severe neonatal hypoglycemia.
Prabudh Goel, Subhasis Roy Choudhury
doaj +1 more source

