Results 91 to 100 of about 71,787 (267)
New Scientist, 2020 A young couple in need of a starter home meet an estate agent who is very definitely not what he seems, and nor is the estate he shows them. Vivarium packs a powerful punch, says Simon Ings.
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Lipid Nanoparticle Co‐Delivery of mRNA and a Small Molecule Drug for Oral Cancer Chemoimmunotherapy
Advanced Materials, EarlyView.Co‐encapsulation of p53 mRNA and the small molecule ciclopirox within a lipid nanoparticle yields an all‐in‐one chemoimmunotherapy for oral squamous cell carcinoma. The platform engages caspase‐driven apoptosis in cancer cells while repolarizing tumor‐associated macrophages, achieving tumor reduction in both p53‐susceptible and p53‐resistant models and
Marshall S. Padilla +15 more
wiley +1 more source
Resolving Heterogeneity of Targeted Lipid Nanoparticles Through Solution‐Based Biophysical Analyses
Advanced Materials, EarlyView.AF4‐UV‐DLS‐MALS‐SAXS resolves previously inaccessible targeted lipid nanoparticle (tLNP) subpopulations that differ in size, shape, and composition. Correlation of subpopulation‐resolved biophysical properties with in vivo RNA delivery reveals that targeted placental transfection is associated with distinct tLNP subpopulations rather than ensemble ...
Hannah C. Geisler +14 more
wiley +1 more source
Physical Review DRecently, we introduced a symmetry on the structure of angular momentum that interchanges internal and external degrees of freedom. The spin-orbit duality is a holographic map that projects a massive theory in four-dimensional flat spacetime onto the three-dimensional S2×R null infinity.
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Advanced Materials, EarlyView.Fully recombinant protein‐based biomaterials execute complex Boolean logic for user‐programmable material degradation and concomitant therapeutic cargo release. Biologics, such as growth factors, can be incorporated within the crosslinkers as “drugamers”, while encapsulated cells can be released according to nested YES/OR/AND‐type logical operations ...
Murial L. Ross +3 more
wiley +1 more source
All-optical processors by 3D printable photochromic materials
Light: Science & ApplicationsDeveloping new responsive materials whose physico-chemical properties can be controlled and tailored by external stimuli is fundamental for many modern technologies.
Francesca D’Elia +4 more
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BiologyBrain plasticity is often described as the capacity of the nervous system to change in response to development, experience, injury, disease, or treatment.
Alessandro Avitabile +4 more
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Topology‐Orchestrated Multi‐physical Energy Control in Turtle Shell‐Inspired Metamaterials
Advanced Materials, EarlyView.A turtle shell‐inspired lattice metamaterial efficiently manages acoustic, fluid‐thermal, and mechanical energy flows simultaneously. The unique hybrid‐coupling architecture achieves superior sound attenuation via pore‐cavity resonance, facilitates effective airflow transport, and maximizes mechanical energy absorption through multistage cell ...
Xi Wang +3 more
wiley +1 more source
Escaping the Scaling Relationships in Oxygen Reduction Catalysis: Implications for PEM Fuel Cells
Advanced Materials, EarlyView.Escaping the scaling relationships of the oxygen reduction reaction is vital for hydrogen fuel cells. This outlook examines how interfacial heterogeneity, spanning the subsurface lattice, chemisorption layer, and near‐interface solvation volume, mechanistically decouples intermediate binding energetics.
Muhammad Bilal Wazir +2 more
wiley +1 more source
Towards AI-driven autonomous growth of 2D materials based on a graphene case study
Communications PhysicsThe scalable synthesis of two-dimensional (2D) materials remains a key challenge for their integration into solid-state technology. While exfoliation techniques have driven much of the scientific progress, they are impractical for large-scale ...
Leonardo Sabattini +9 more
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