Results 161 to 170 of about 512,149 (288)

Rescuing Mitochondrial Dysfunction in Macrophages Prevents Osteonecrosis of the Jaw in Anti‐Resorptive Therapy

Advanced Science, EarlyView.
Schematic model showing the suggested mechanism that ZA induces classical activation of macrophages by impairing mitochondrial biofunction and inhibiting mitochondrial clearance to contribute to the pathological process of BRONJ. RAPA‐loaded nanoparticles ZDPR has shown potential in alleviating BRONJ lesions as well as treating osteoporosis or ...
Hang Zhang, Xin Shen, Haiyang Liu, Xinxi Yuan, Mumin Cao, Xuepeng Lv, Ziji Ling, Songsong Guo, Rongyao Xu, Xiang Li, Hongbing Jiang   +10 more
wiley   +1 more source

Prevalence and related influencing factors of depression symptoms among empty-nest elderly in China. [PDF]

Sci Rep
Li D, Long Z.
europepmc   +1 more source

Data‐Driven Feedback Identifies Focused Ultrasound Exposure Regimens for Improved Nanotheranostic Targeting of the Brain

Advanced Science, EarlyView.
Machine learning models predict in real time the onset of harmful microbubble collapse during microbubble‐enhanced focused ultrasound (MB‐FUS) and enable dynamic adjustment of sonication to prevent cavitation‐induced damage. This predictive control expands the safe operating window for bloodbrain barrier opening, enhancing nanoparticle delivery and ...
Hohyun Lee, Victor Menezes, Shiqin Zeng, Chulyong Kim, Cynthia M. Baseman, Jae Hyun Kim, Samhita Padmanabhan, Pranav Premdas, Naima Djeddar, Anton Bryksin, Nikhil Pandey, Pavlos Anastasiadis, Anthony J. Kim, Tobey J. MacDonald, Chetan Bettegowda, Graeme F. Woodworth, Felix J. Herrmann, Costas Arvanitis   +17 more
wiley   +1 more source

Winter food sources for the Grey-headed Woodpecker (<i>Picus canus</i>) in South Korea using faecal analysis in nest boxes. [PDF]

Biodivers Data J
Lee SY, Hong EJ, Lee EJ, Lee J, Sung H.
europepmc   +1 more source

Macrophage TRIM21 Inhibition Ameliorates Murine Acute Pancreatitis via PHB2‐Mediated Mitochondrial Stabilization

Advanced Science, EarlyView.
Macrophage‐derived TRIM21 drives the progression of AP via ubiquitin‐proteasome‐mediated degradation of PHB2, leading to impaired PHB2‐mediated mitophagy. Therefore, accumulation of cytosolic mtDNA hyperactivates the cGAS‐STING signaling axis, thereby amplifying inflammatory cascades.
Yansong Xu, Yuansong Sun, Xin Zhou, Kai Song, Chunlin Yin, Zhaohua Wang, Fei Xie, He Li   +7 more
wiley   +1 more source

Thermal Ecology and Homeostasis in Colonies of the Neotropical Arboricolous Ant Azteca chartifex spiriti (Formicidae: Dolichoderinae). [PDF]

Insects
Dos Santos JT, Koch EBA, Dos Santos JL, Bomfim LDS, Delabie JHC, Mariano CDSF.   +5 more
europepmc   +1 more source

A Tangentially Sensitive Tactile Sensor Reveals the Stick‐Slip Mechanism and Enhances Robotic Tactile Sensing

Advanced Science, EarlyView.
An ultralight, multilayer anisotropic tactile sensor—an artificial Pacinian corpuscle—exhibits ultrahigh tangential sensitivity (1022 kPa−1) and spatiotemporal sensing. It discriminates static, sliding, and rolling contacts, detects incipient stick–slip via high‑frequency signatures, and enhances robotic touch (100%/98.18% accuracy for active/passive ...
Jinghui Wang, Xiaoyu Liu, Yujiao Du, Yepu Chen, Jieyi Guo, Linyuan Fan, Min Tang, Xiaofeng Qiao, Yuanjie Zhu, Zhiyang Zhang, Chaojie Dong, Lizhen Wang, Yubo Fan   +12 more
wiley   +1 more source

Hepatocyte BPGM Induces RET Lactylation and Macrophage Reprogramming to Promote Tumorigenesis in Hepatocellular Carcinoma

Advanced Science, EarlyView.
Mechanistic schematic diagram.BPGM promotes the expression level of RET by increasing the lactylation of RET‐K549 and inhibiting its ubiquitination levels in HCC cells. Furthermore, BPGM in HCC cells could also promote M2 polarization in macrophages through lactate secretion. Both of the mechanisms could promote the progression of HCC. ABSTRACT Aerobic
Jiajia Zhang, Lu Shi, Liangliang Lin, Yang Zhang, Miao Zhang, Lili Wu, Yong Xia, Yaqiong Zhang, Peng Han, Likun Zhuang, Liang Shi   +10 more
wiley   +1 more source

Reproductive Success and Diet of the Swainson's Hawk (<i>Buteo swainsoni</i>) in the Grasslands of Janos, Chihuahua, Mexico. [PDF]

Animals (Basel)
Maldonado NNC, Lozoya CJV, Nieto JC, Kerstupp AO, Aymá GR, Velasco AG, Rojas JIG.   +6 more
europepmc   +1 more source

NIR Light‐Driven Photocatalytic Antibacterial Hydrogels for Synergistic MRSA Biofilm Eradication and Wound Regeneration

Advanced Science, EarlyView.
The nanohybrid hydrogel (Fe‐BOS@C/H Gel) is composed of Fe‐Bi2O2‐XS (Fe‐BOS) photocatalysts and CS‐ADH/OHA (C/H) hydrogel. Fe‐BOS photocatalysts achieve near‐infrared (NIR) light‐driven antibacterial photocatalytic/mild photothermal therapy (APCT/MPTT), effectively eliminating methicillin‐resistant Staphylococcus aureus (MRSA) biofilms. The degradation
Dong Mo, Yujia Wei, Meng Pan, Wen Chen, Yun Yang, Kang Li, Xicheng Li, Jianan Li, Qingya Liu, Hanzi Deng, Mei Zhu, Zhenpeng Zhang, Zhaolin Xiao, Zhiyong Qian   +13 more
wiley   +1 more source