A new family of diverse skin peptides from the microhylid frog genus phrynomantis [PDF]
, 2020 A wide range of frogs produce skin poisons composed of bioactive peptides for defence against pathogens, parasites and predators. While several frog families have been thoroughly screened for skin-secreted peptides, others, like the Microhylidae, have ...
Ballet, Steven +7 more
core +1 more source
Structure- and context-based analysis of the GxGYxYP family reveals a new putative class of glycoside hydrolase. [PDF]
, 2014 BackgroundGut microbiome metagenomics has revealed many protein families and domains found largely or exclusively in that environment. Proteins containing the GxGYxYP domain are over-represented in the gut microbiota, and are found in Polysaccharide ...
Chang, Yuanyuan +5 more
core +2 more sources
Frog foams and natural protein surfactants [PDF]
, 2017 Foams and surfactants are relatively rare in biology because of their potential to harm cell membranes and other delicate tissues. However, in recent work we have identified and characterized a number of natural surfactant proteins found in the foam ...
Cooper, Alan +3 more
core +1 more source
Dissection of GTPase activating proteins reveals functional asymmetry in the COPI coat of budding yeast. [PDF]
, 2019 The Arf GTPase controls formation of the COPI vesicle coat. Recent structural models of COPI revealed the positioning of two Arf1 molecules in contrasting molecular environments.
Arakel, E. +5 more
core +1 more source
The structure of latherin, a surfactant allergen protein from horse sweat and saliva [PDF]
, 2013 Latherin is a highly surface-active allergen protein found in the sweat and saliva of horses and other equids. Its surfactant activity is intrinsic to the protein in its native form, and is manifest without associated lipids or glycosylation.
Alan Cooper +6 more
core +1 more source
Comparative Analysis of WRKY Genes Potentially Involved in Salt Stress Responses in Triticum turgidum L. ssp. durum [PDF]
, 2017 WRKY transcription factors are involved in multiple aspects of plant growth, development and responses to biotic stresses. Although they have been found to play roles in regulating plant responses to environmental stresses, these roles still need to be ...
Berges, Hélène +5 more
core +13 more sources
VAPB/ALS8 interacts with FFAT-like proteins including the p97 cofactor FAF1 and the ASNA1 ATPase [PDF]
, 2014 BACKGROUND: FAF1 is a ubiquitin-binding adaptor for the p97 ATPase and belongs to the UBA-UBX family of p97 cofactors. p97 converts the energy derived from ATP hydrolysis into conformational changes of the p97 hexamer, which allows the dissociation of ...
Alexandru, Gabriela +7 more
core +4 more sources
Disease progression in Plasmodium knowlesi malaria is linked to variation in invasion gene family members. [PDF]
, 2014 Emerging pathogens undermine initiatives to control the global health impact of infectious diseases. Zoonotic malaria is no exception. Plasmodium knowlesi, a malaria parasite of Southeast Asian macaques, has entered the human population. P.
A Berry +61 more
core +3 more sources
Structural Evidence for the Tetrameric Assembly of Chemokine CCL11 and the Glycosaminoglycan Arixtra™. [PDF]
, 2013 Understanding chemokine interactions with glycosaminoglycans (GAG) is critical as these interactions have been linked to a number of inflammatory medical conditions, such as arthritis and asthma.
Dykstra, Andrew B +2 more
core +2 more sources
Dissecting protein loops with a statistical scalpel suggests a functional implication of some structural motifs. [PDF]
, 2011 International audienceUNLABELLED: ABSTRACT: BACKGROUND: One of the strategies for protein function annotation is to search particular structural motifs that are known to be shared by proteins with a given function.
Regad, Leslie +2 more
core +3 more sources