Results 131 to 140 of about 15,648,464 (247)
Advanced Science, EarlyView.The protein aggregates and gene expression in the middle temporal gyrus (MTG) and somatosensory cortex (SOM) of the postmortem brains of 13 Alzheimer's disease patients were studied in detail, revealing that small hyperphosphorylated tau aggregates increase with Braak stage driven by microglial inflammation.
Elizabeth A. English +9 more
wiley +1 more source
Prediction of a Small Area Mean for an Infinite Population when the Variance Components Are Random [PDF]
In this paper, we propose a new model with random variance components for estimating small area characteristics. Under the proposed model, we derive the empirical best linear unbiased estimator, an approximation to terms of order and an estimator whose ...
Stefan, Marius
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Advanced Science, EarlyView.Biomineralization underpins skeletal development, yet its molecular control remains incompletely understood. Using a novel murine knockout model, this study reveals the essential and complementary roles of PHOSPHO1 and TNAP in postnatal skeletal development.
Lucie E. Bourne +15 more
wiley +1 more source
Bootstrap for estimating the mean squared error of the spatial EBLUP [PDF]
This work assumes that the small area quantities of interest follow a Fay-Herriot model with spatially correlated random area effects. Under this model, parametric and nonparametric bootstrap procedures are proposed for estimating the mean squared error ...
Isabel Molina +2 more
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Advanced Science, EarlyView.Main Raman signals in RNA, related to helical backbone, ribofuranose ring, and nitrogenous bases, are affected by secondary structures that cause hyperchromic effects and significantly alter the Raman intensity. ABSTRACT Raman spectra of RNA nucleotide strands extracted from 20 SARS‐CoV‐2 strains, including the original Japanese isolate, Alpha, Beta ...
Giuseppe Pezzotti +11 more
wiley +1 more source
Multi-sensor data-driven intelligent product interaction fault self-diagnosis system
Discover ComputingIntelligent fault diagnosis is crucial for the safety and reliability of dynamic smart manufacturing systems. Existing single-sensor approaches do not model complex, multi-dimensional interactions between robotic components during dynamic interactions ...
Bei Hu
doaj +1 more source
Closing the evidence gap: reddemcee, a fast adaptive parallel tempering sampler
Astronomy & AstrophysicsContext. Markov chain Monte Carlo (MCMC) excels at sampling complex posteriors, but traditionally lags behind nested sampling in accurate evidence estimation, which is crucial for model comparison in astrophysical problems. Aims.
Peña R Pablo A., Jenkins James S.
doaj +1 more source
Integrating Kinetics into Synthetic Studies via Adaptable Concentration‐Dependent Yield Analysis
Advanced Science, EarlyView.A method to derive kinetic parameters from synthetic studies was developed and named concentration‐dependent yield analysis (CYAN). Using numerical Euler integration for kinetic regression, CYAN was proven adaptable to chemical and operational considerations and revealed unexpected template effects of a transition metal that mediated competitive ...
Xinyi Xiao +4 more
wiley +1 more source
BioengineeringThe urinary sodium-to-potassium (Na/K) ratio is a clinically established predictor of blood pressure and cardiovascular risk. This study aimed to develop and rigorously evaluate machine learning models for estimating the urinary Na/K ratio using four ...
Emi Yuda, Itaru Kaneko, Daisuke Hirahara
doaj +1 more source
On the J-test for nonnested hypotheses and Bayesian extension [PDF]
Davidson and MacKinnon’s J-test was developed to test non-nested model specification. In empirical applications, however, when the alternate specifications fit the data well the J test may fail to distinguish between the true and false models: the J test
Krieg, John, Rao, Surekha, Ghali, Moheb
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