Circulating cell‐free mitochondrial DNA provides a robust, noninvasive platform for early detection and histological subtyping of esophageal cancer. This large multi‐center study validates consistently high accuracy across ethnically and geographically diverse cohorts, demonstrating strong potential to transform clinical management. ABSTRACT Esophageal
Yue Liu +15 more
wiley +1 more source
Multilevel IRT Modeling in Practice with the Package mlirt [PDF]
Variance component models are generally accepted for the analysis of hierarchical structured data. A shortcoming is that outcome variables are still treated as measured without an error.
Jean-Paul Fox
core
A taxonomy of reliability indices for cluster-level constructs measured by multiple individual-level indicators. [PDF]
Jorgensen TD, Jak S.
europepmc +1 more source
Model error space and data assimilation in the Mediterranean Sea and nested models
In this work, we implemented the GHER hydrodynamic model in the Gulf of Lions (resolution 1/100 °). This model is nested interactively in another model covering the North-Western basin of the Mediterranean Sea (resolution 1/20°), itself nested in a model covering the whole basin (1/4 °).
openaire +1 more source
From Artificial to Embodied and Physical Intelligence in Smart Manufacturing
Smart manufacturing is reframed through complementary artificial, embodied, and physical intelligence, spanning computational reasoning, perception‐action coupling, and material‐level adaptation. Their integration across design, fabrication, operation, and maintenance reveals how intelligence can be co‐designed across algorithms, embodied agents, and ...
Kang Wang +9 more
wiley +1 more source
Testing a dual-process-inspired questionnaire-primary residual framework for personality prediction: an exploratory study with static line drawings. [PDF]
Weng L, Shi Y.
europepmc +1 more source
In Sertoli cells of iNOA testes, downregulation of FADS2 activates STING, promoting collagen deposition and peritubular fibrosis while increasing germ‐cell susceptibility to necroptosis. Supplementation with FADS2‐derived PUFAs (GLA and DHA) inhibits STING, alleviates collagen accumulation, and facilitates the recovery of spermatogenesis.
Jiajing Lin +15 more
wiley +1 more source
Study-Grouped Predictive Toxicology of In Vitro Polystyrene Micro- and Nanoplastic Cytotoxicity: Geometry-Derived Administered-Dose Metrics and a Nanoscale-Restricted Sensitivity Analysis. [PDF]
Özkan Vardar D, Vardar N.
europepmc +1 more source
A computed tomography lesion foundation model, built by sequential self‐supervised pretraining on generic and hepatocellular carcinoma‐specific lesion images, non‐invasively assesses microvascular invasion and pathological grade from contrast‐enhanced CT and stratifies postoperative recurrence risk.
Wei Xia +9 more
wiley +1 more source
Estimation with the Nested Logit Model: Specifications and Software Particularities [PDF]
Due to its ability to allow and account for similarities betweenpairs of alternatives, the nested logit model is increasingly used in practical applications.
Nadja Silberhorn +2 more
core

