Results 161 to 170 of about 16,074,262 (296)

Noninvasive Detection and Subtyping of Esophageal Cancer by Circulating Cell‐Free mtDNA Fragmentomics: A Multi‐Center Validation Study

open access: yesAdvanced Science, EarlyView.
Circulating cell‐free mitochondrial DNA provides a robust, noninvasive platform for early detection and histological subtyping of esophageal cancer. This large multi‐center study validates consistently high accuracy across ethnically and geographically diverse cohorts, demonstrating strong potential to transform clinical management. ABSTRACT Esophageal
Yue Liu   +15 more
wiley   +1 more source

Multilevel IRT Modeling in Practice with the Package mlirt [PDF]

open access: yes
Variance component models are generally accepted for the analysis of hierarchical structured data. A shortcoming is that outcome variables are still treated as measured without an error.
Jean-Paul Fox
core  

Model error space and data assimilation in the Mediterranean Sea and nested models

open access: yes, 2007
In this work, we implemented the GHER hydrodynamic model in the Gulf of Lions (resolution 1/100 °). This model is nested interactively in another model covering the North-Western basin of the Mediterranean Sea (resolution 1/20°), itself nested in a model covering the whole basin (1/4 °).
openaire   +1 more source

From Artificial to Embodied and Physical Intelligence in Smart Manufacturing

open access: yesAdvanced Science, EarlyView.
Smart manufacturing is reframed through complementary artificial, embodied, and physical intelligence, spanning computational reasoning, perception‐action coupling, and material‐level adaptation. Their integration across design, fabrication, operation, and maintenance reveals how intelligence can be co‐designed across algorithms, embodied agents, and ...
Kang Wang   +9 more
wiley   +1 more source

FADS2‐STING Signaling in Sertoli Cells Orchestrates Collagen Deposition and Germ Cell Necroptosis in Idiopathic Non‐Obstructive Azoospermia

open access: yesAdvanced Science, EarlyView.
In Sertoli cells of iNOA testes, downregulation of FADS2 activates STING, promoting collagen deposition and peritubular fibrosis while increasing germ‐cell susceptibility to necroptosis. Supplementation with FADS2‐derived PUFAs (GLA and DHA) inhibits STING, alleviates collagen accumulation, and facilitates the recovery of spermatogenesis.
Jiajing Lin   +15 more
wiley   +1 more source

A CT Lesion Foundation Model for Non‐Invasive Assessment of Hepatocellular Carcinoma Aggressiveness and Prediction of Recurrence Risk

open access: yesAdvanced Science, EarlyView.
A computed tomography lesion foundation model, built by sequential self‐supervised pretraining on generic and hepatocellular carcinoma‐specific lesion images, non‐invasively assesses microvascular invasion and pathological grade from contrast‐enhanced CT and stratifies postoperative recurrence risk.
Wei Xia   +9 more
wiley   +1 more source

Estimation with the Nested Logit Model: Specifications and Software Particularities [PDF]

open access: yes
Due to its ability to allow and account for similarities betweenpairs of alternatives, the nested logit model is increasingly used in practical applications.
Nadja Silberhorn   +2 more
core  

Home - About - Disclaimer - Privacy