Results 151 to 160 of about 15,648,464 (247)

TESTING THE NEG MODEL : FURTHER EVIDENCE FROM PANEL DATA [PDF]

open access: yes
Local wage variations in the UK are explained by two non-nested rival hypotheses. The first derives from new economic geography theory, in which wages depend on market access.
Bernard FINGLETON
core  

LLMs as Representation Generators for Gradient‐Free Scientific Optimization: A Case Study in Battery Fast Charging

open access: yesAdvanced Science, EarlyView.
Large language models serve as representation generators for gradient‐free scientific optimization. Two complementary approaches produce executable battery‐charging policies either directly or through LLM‐designed neural representations coupled to Bayesian optimization.
Ge Lei   +3 more
wiley   +1 more source

A Generalizable Multimodal Model for Treatment‐Stratified Risk and Survival Assessment under Real‐World Constraints: A Multi‐Center Study of Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
DAIMS is a multimodal model for treatment stratified risk and survival assessment in colorectal cancer. Training draws on pathology, genomics, and clinical reports, yet inference requires only whole slide images, and adaptation to new cohorts proceeds without target survival outcomes.
Chuangjie Cao   +15 more
wiley   +1 more source

ACAT1‐Mediated SP1‐K694 Lactylation Promotes M1 Macrophage Polarization via TREM1 Transcription in COPD

open access: yesAdvanced Science, EarlyView.
Upon cigarette smoke exposure(CSE), LDHA expression is increased in lung macrophages, promoting the conversion of pyruvate to lactate and elevating the lactylation level of SP1 at the K694 site. This, in turn, enhances SP1 enrichment at the TREM1 promoter, increases TREM1 expression, promoted M1 macrophage polarization, and triggers the secretion of ...
Ling Lin   +5 more
wiley   +1 more source

Vine‐Inspired Soft Robotics: Materials, Actuations, and Emerging Applications

open access: yesAdvanced Science, EarlyView.
Vine‐inspired robots grow from the tip, enabling navigation through confined spaces with minimal disturbance. This Review summarizes material and actuation strategies for vine‐inspired growth, key functions including steering, retraction, attachment, branching, and variable stiffness, and emerging applications spanning medical intervention, confined ...
Jiahao Wu   +7 more
wiley   +1 more source

CALIBRATING THE INTERCITY HIGH SPEED RAIL (HSR) CHOICE MODEL FOR THE RICHMOND-WASHINGTON, D.C. CORRIDOR [PDF]

open access: yes
This study aims to quantitatively investigate how the introduction of high-speed rail (HSR) influences traveler’s choice behavior. The study focuses on recalibrating the Florida-based HSR choice model to fit the intercity travel northward from Richmond ...
Xueming CHEN
core  

Soil pH Amelioration Synergizes Carbon Accrual with Yield Gains Under Organic Substitution

open access: yesAdvanced Science, EarlyView.
Soil pH shifts towards neutrality in both acidic and alkaline soils under organic substitution. A global synthesis links pH amelioration to soil organic carbon accrual through enhanced microbial biomass after accounting for added organic carbon and its interaction with pH. This pH amelioration‐shared soil organic carbon accrual accounts for 5.1–8.6% of
Xunzhuo Dong   +7 more
wiley   +1 more source

Multilevel IRT Modeling in Practice with the Package mlirt [PDF]

open access: yes
Variance component models are generally accepted for the analysis of hierarchical structured data. A shortcoming is that outcome variables are still treated as measured without an error.
Jean-Paul Fox
core  

Transformer‐Based PET/CT Fusion Enables Preoperative Prediction and Prognostic Stratification of Spread Through Air Spaces in Lung Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
An eight‐stream 2.5D Transformer integrates complementary PET metabolic and CT morphologic information to estimate spread‐through‐air‐spaces risk before surgery in lung adenocarcinoma. The model generalizes across independent centers, while its continuous risk score independently stratifies progression‐free survival, supporting further prospective ...
Xin‐Yu Zhu   +7 more
wiley   +1 more source

Yoda1‐Functionalized Nanozymes Coordinate Piezo1 Activation and Mitochondrial Protection to Reprogram the Diabetic Osteoimmune Micromilieu and Promote Vascularized Bone Repair

open access: yesAdvanced Science, EarlyView.
Diabetic bone defects remain a critical clinical challenge. A 3D‐printed BCPG‐MF@Y scaffold, embedding Yoda1‐functionalized manganese dioxide‐ferritin nanozymes, scavenges mtROS, suppresses the cGAS–STING pathway, and reverses cellular senescence, while Yoda1 activates Piezo1 to direct BMSCs fate to synergistically reprogram the osteoimmune ...
Qing‐Song Deng   +16 more
wiley   +1 more source

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