Results 31 to 40 of about 15,053,099 (290)

On testing random effects in the nested-error regression model

open access: yesCommunications in Statistics - Simulation and Computation, 2017
We derive an exact F-test for random effects in the nested-error regression model. The derivation utilizes a matrix decomposition that offers a transformation of the response vector into two indepe...
Hall, Peter, Maiti, Tapabrata
openaire   +6 more sources

Simultaneous estimation under nested error regression model

open access: yes, 2004
Zhang (2003) proposed a frequentist method of simultaneous small area estimation under hierarchical models. This can be useful when various ensemble characteristics of the small area parameters are of interest in addition to area-specific prediction.
Zhang, Li-Chun
openaire   +2 more sources

A principled approach to programming with nested types in Haskell [PDF]

open access: yes, 2009
Initial algebra semantics is one of the cornerstones of the theory of modern functional programming languages. For each inductive data type, it provides a Church encoding for that type, a build combinator which constructs data of that type, a fold ...
Ghani, Neil, Johann, Patricia
core   +4 more sources

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

WaterLynn/Bayesian-Nested-Patch-Occupancy-Model: Bayes PIT Tag Model for Ecol. App. Manuscript

open access: yes, 2020
Code for Waterhouse, L., J. White, K. See, A. Murdoch, B. Semmens, (2020). A Bayesian nested patch occupancy model to estimate steelhead movement and abundance.
Lynn Waterhouse
core   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak   +4 more
wiley   +1 more source

Multilevel IRT Modeling in Practice with the Package mlirt

open access: yesJournal of Statistical Software, 2007
Variance component models are generally accepted for the analysis of hierarchical structured data. A shortcoming is that outcome variables are still treated as measured without an error.
Jean-Paul Fox
doaj  

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