Results 111 to 120 of about 1,409,120 (251)
Advanced Science, EarlyView.Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon +27 more
wiley +1 more source
Nesting and Scheduling analysis in additive manufacturing
reservedLo scopo dell’industria 4.0 è quello di interconnettere e automatizzare una serie di tecnologie, chiamate tecnologie abilitanti, con il fine di aumentare la produttività e la qualità del prodotti.
PADOVAN, RICCARDO
core
Closing the Empirical Loop: Autonomous AI Agents Conduct End‐to‐end Research With Human Participants
Advanced Science, EarlyView.A multi‐agent AI system autonomously executes the complete scientific workflow, from hypothesis to manuscript, across three psychological studies involving 288 participants. The system designs experiments, collects real world data, develops analysis pipelines, and writes manuscripts with theoretical rigor comparable to experienced researchers.
Gabrielle Wehr +6 more
wiley +1 more source
SociobiologyBees are one of the most important ecological (as pollinators of cultivated and wild plant species) and economic (fruits and seeds produced by pollination, and several bee products commercialized and consumed) groups of insects.
Celso Feitosa Martins +2 more
doaj +1 more source
A Panel of Circulating Exosomal sncRNAs Associated With Lung Cancer Risk up to 10 Years in Advance
Advanced Science, EarlyView.Lung cancer is often diagnosed too late, and current screening overlooks many people at risk. In a long‐term study of smokers, a panel of small non‐coding RNAs carried in blood exosomes signals elevated lung cancer risk up to ten years before diagnosis, pointing toward a blood‐based tool for earlier risk detection.
Zhuokun Feng +12 more
wiley +1 more source
Nesting-Algorithmus für irreguläre einfache Formen auf ebenen Flächenstücken
, 2013 Nesting, C-obstacle, Minkowski, zero surfaces, cutting optimization. - The leather processing industry requires considerable amounts of leather. The desire from an economic perspective is, that the leather waste is small.
Hagemann, Ralf
core
Advanced Science, EarlyView.Hypoxia‐adaptive bioelectronics based on poly(3,4‐ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS)/polydopamine (PDA)/enzyme biocomposites couple O2‐centric biosensing with embedded O2 therapy to address oxygen‐deficient chronic wounds. Local O2 provision restores enzyme‐based metabolite sensing, while catalase‐mediated oxygen generation and
Songrui Liu +16 more
wiley +1 more source
SociobiologyMegachile disjuncta is a common solitary bee widely distributed and has been reported as an effective pollinator of legume crops in India. A study was conducted using the trap-nest methodology during 2023, and the new information on nesting behaviour ...
Pampareddy +4 more
doaj +1 more source
Advanced Science, EarlyView.FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni +17 more
wiley +1 more source
Advanced Science, EarlyView.PTEN knockdown activates AKT phosphorylation, promoting Nrf2 nuclear translocation and STAT3 activation, which upregulates GPX4 and antioxidant enzymes HO‐1, SOD1, SOD2, and NQO1. These coordinated changes reduce lipid peroxidation and ROS, inhibit ferroptosis, and ultimately ameliorate cognitive impairment in APP/PS1 transgenic mice, highlighting a ...
Da‐Wei Wang +5 more
wiley +1 more source