Results 51 to 60 of about 145,780 (325)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Composition with Target Constraints [PDF]
, 2010 It is known that the composition of schema mappings, each specified by source-to-target tgds (st-tgds), can be specified by a second-order tgd (SO tgd). We consider the question of what happens when target constraints are allowed.
A. Deutsch, L. Popa, and V. Tannen +12 more
core +4 more sources
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Nested Quantum Annealing Correction
, 2015 We present a general error-correcting scheme for quantum annealing that allows for the encoding of a logical qubit into an arbitrarily large number of physical qubits.
Albash, Tameem +2 more
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Nested distance for stagewise-independent processes
, 2017 24 pages, 6 ...
Cabral, Filipe Goulart +1 more
openaire +2 more sources
The loggerhead sea turtle (Caretta caretta) on Sal Island, Cape Verde : nesting activity and beach surveillance in 2009 [PDF]
, 2010 Surveys for Caretta caretta nesting activities were performed during the nesting seasons from the middle of June to end of October 2009 on Sal Island, Cape Verde.
Cozens, Jacquie +2 more
core
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Nest site availability and niche differentiation between two cavity‐nesting birds in time and space
Ecology and Evolution, 2019 Niche differentiation is a key concept in the field of ecology and refers to the process by which competing species within an ecological community partition utilization of environmental resources to achieve coexistence.
Ping Ye, Canchao Yang, Wei Liang
doaj +1 more source
Global Ecology and Conservation, 2022 Global warming is affecting habitat quality and availability on our planet and some species are predicted or are by now changing their distribution range.
Sandra Hochscheid +15 more
doaj +1 more source