Results 61 to 70 of about 145,780 (325)

Texture Modelling with Nested High-order Markov-Gibbs Random Fields

, 2015
Currently, Markov-Gibbs random field (MGRF) image models which include high-order interactions are almost always built by modelling responses of a stack of local linear filters.
Gimel'farb, Georgy, Riddle, Patricia, Versteegen, Ralph   +2 more
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Repair Method and Muéganos Structure Applied to the Nesting Problem in Finite Materials

Applied Sciences, 2023
During an optimization process which uses a metaheuristic strategy applied to the nesting problem, it is required to apply a repair method if the random solution contains overlapping items.
Anabel Rodríguez, Francisco Cuevas, Daniela Esparza   +2 more
doaj   +1 more source

Wind Speed Modeling by Nested ARIMA Processes [PDF]

Energies, 2018
Wind speed modelling is of increasing interest, both for basic research and for applications, as, e.g., for wind turbine development and strategies to construct large wind power plants. Generally, such modelling is hampered by the non-stationary features of wind speed data that, to a large extent, reflect the turbulent dynamics in the atmosphere.
So-Kumneth Sim, Philipp Maass, Pedro G. Lind   +2 more
openaire   +2 more sources

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source

Nest site selection and fidelity of European pond turtle (Emys orbicularis) population of Babat Valley (Gödöllő, Hungary)

Frontiers in Zoology
Background The conservation of aquatic and semiaquatic turtles requires knowledge of the area and vegetation structure of habitat used for nesting, and nesting migration route. We aimed to survey the effects of habitat features to the nest site selection,
István Kiss, Gergő Erdélyi, Borbála Szabó   +2 more
doaj   +1 more source

Marginalised Gaussian Processes with Nested Sampling

, 2020
Gaussian Process (GPs) models are a rich distribution over functions with inductive biases controlled by a kernel function. Learning occurs through the optimisation of kernel hyperparameters using the marginal likelihood as the objective. This classical approach known as Type-II maximum likelihood (ML-II) yields point estimates of the hyperparameters ...
Simpson, Fergus, Lalchand, Vidhi, Rasmussen, Carl Edward   +2 more
openaire   +2 more sources

Unconventional Superconductivity and Density Waves in Twisted Bilayer Graphene

, 2018
We study electronic ordering instabilities of twisted bilayer graphene with $n=2$ electrons per supercell, where correlated insulator state and superconductivity are recently observed.
Fu, Liang, Isobe, Hiroki, Yuan, Noah F. Q.   +2 more
core   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source