Results 51 to 60 of about 972,559 (290)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Engineering, 2016 The increasing pace of urbanization means that cities and global organizations are looking for ways to increase energy efficiency and reduce emissions.
Jean-Ann James +4 more
doaj +1 more source
Energies, 2023 Renewable Energy Sources (RES) have been gaining popularity on a continuous basis and the current global political situation is only accelerating energy transformation in many countries.
Dariusz Kurz, Agata Nowak
doaj +1 more source
Co-optimizing Behind-The-Meter Resources under Net Metering
2023 IEEE Texas Power and Energy Conference (TPEC), 2023 8 pages, 4 figures, 4 ...
Ahmed S. Alahmed, Lang Tong 0001
openaire +2 more sources
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Energies, 2023 Recently, thanks to various support mechanisms, residential photovoltaics (PVs) for self-consumption are proliferating at a rapid pace. The net-metering scheme, one of the prevailing support mechanisms for self-consumption PVs, contributes to the ...
Junhyung Kim +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Evaluation of Temporary Ramp Metering for Work Zones, 2012 [PDF]
, 2012 Ramp metering has been successfully implemented in many states to improve traffic operations on freeways. Studies have documented the positive mobility and safety benefits of ramp metering.
core
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source