Results 61 to 70 of about 5,577,015 (290)
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Renewable Energy FocusFederal and state decarbonization goals have led to numerous financial incentives and policies designed to increase access and adoption of renewable energy systems.
Jessica Kerby, B. Tarekegne
semanticscholar +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
The effect of net metering methods on prosumer energy settlements
, 2021 Net metering is a well-known mechanism, where only energy exchanges of prosumers with the grid are accounted for in settlements. What is less known is the subtleness of the metering practices of energy suppliers behind the reported energy values.
C. Ziras, Lisa Calearo, Mattia Marinelli
semanticscholar +1 more source
, 2009 This map shows states with net metering schemes to measure a site's electricity generation versus a site's electricity production, with customers only paying for the net electricity ...
Pew Center on Global Climate Change
core
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
Frontiers in Energy ResearchThe decarbonization of islanded village energy systems is constrained not only by the intermittency of renewable generation but also by the regulatory frameworks that govern grid interaction. This study develops and validates a policy-constrained Genetic
Nikolaos Sifakis +3 more
doaj +1 more source
Energies, 2022 The increased popularity of small-scale DER has replaced the well-established concept of conventional generating plants around the world. In the present energy scenario, a significant share of energy production now comes from the grid integrated DERs ...
Harpreet Sharma +8 more
doaj +1 more source