Results 51 to 60 of about 1,337 (263)
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
EnergiesThis paper addresses the issue of the abolition of annual net metering in Slovenia and compares the electric energy costs for the studied active user after the abolition. The article also provides an exploration of the role played by an aggregator, which
Eva Tratnik, Miloš Beković
doaj +1 more source
Energies, 2019 In order to improve energy efficiency, the Croatian government introduced an individual metering obligation for all district heat network users. The purpose of the research was to evaluate this policy measure regarding its effects on tenants’ ...
Sunčana Slijepčević +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Sizing Merchant Energy Storage for Maximum Revenues Considering Net Metering and Ancillary Services
IEEE AccessAs prices for energy storage (ES) decline, merchant-owned ES units have an opportunity to be profitable if they earn revenue from multiple streams. Most papers in the literature provide a simplistic view, and do not capture practical tariff structure of ...
Jessie Ma, Bala Venkatesh
doaj +1 more source
Chemical Engineering Transactions, 2019 The Philippine Industrial Sector contributes USD 124x109 (~PHP 6.5x1012) or about 1/3 in the economy. However, the electricity cost, which is 2nd highest in Asia, constitutes up to 10 % of their total operating expenses.
Patrick Gregory Jara +4 more
doaj +1 more source
Detection of False-Reading Attacks in the AMI Net-Metering System
CoRR, 2020 In smart grid, malicious customers may compromise their smart meters (SMs) to report false readings to achieve financial gains illegally. Reporting false readings not only causes hefty financial losses to the utility but may also degrade the grid performance because the reported readings are used for energy management. This paper is the first work that
Mahmoud M. Badr +4 more
openaire +2 more sources
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source