Results 41 to 50 of about 1,337 (263)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Neurodevelopmental and neurocognitive difficulties are prevalent among individuals with sickle cell disease and warrant prompt identification and support. This Special Report provides an executive summary of standards and recommendations for surveillance, screening, and evaluation for development and cognition across the lifespan developed by ...
Alyssa M. Schlenz +12 more
wiley +1 more source
Energies, 2022 The increased popularity of small-scale DER has replaced the well-established concept of conventional generating plants around the world. In the present energy scenario, a significant share of energy production now comes from the grid integrated DERs ...
Harpreet Sharma +8 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Net Metering Prediction in Prosumer Building With Temporal Fusion Transformer Models
IEEE AccessThe growing global demand for electrical energy, together with the significant problem of increasing carbon dioxide emissions, have become urgent issues. The inefficient use of electricity exacerbates these challenges.
Sorawut Jittanon +3 more
doaj +1 more source
Blockchain-Modeled Edge-Computing-Based Smart Home Monitoring System with Energy Usage Prediction
Sensors, 2023 Internet of Things (IoT) has made significant strides in energy management systems recently. Due to the continually increasing cost of energy, supply–demand disparities, and rising carbon footprints, the need for smart homes for monitoring, managing, and
Faiza Iqbal +6 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Frontiers in Energy ResearchThe decarbonization of islanded village energy systems is constrained not only by the intermittency of renewable generation but also by the regulatory frameworks that govern grid interaction. This study develops and validates a policy-constrained Genetic
Nikolaos Sifakis +3 more
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source